PEE - Specimen: Porphyrins Evaluation, Whole Blood

Test Catalog

Test Name

Test ID: PEE    
Porphyrins Evaluation, Whole Blood

Testing Algorithm Delineates situation(s) when tests are added to the initial order. This includes reflex and additional tests.

This test is recommended for screening patients for possible erythropoietic protoporphyria and X-linked dominant protoporphyria. In addition, it can be used for evaluation of iron-deficiency anemia and chronic lead intoxication. Testing begins with total erythrocyte porphyrins. If the result is <80 mcg/dL, it is normal and testing is complete.

 

If the total erythrocyte porphyrin value is > or =80 mcg/dL, the protoporphyrin fractionation (PPFE) assay will automatically be performed at an additional charge. The PPFE test results include free protoporphyrin and zinc-complexed protoporphyrin.

 

The following algorithms are available in Special Instructions:

-Porphyria (Acute) Testing Algorithm

-Porphyria (Cutaneous) Testing Algorithm

Specimen Type Describes the specimen type needed for testing

Whole blood

Necessary Information

Include a list of medications the patient is currently taking.

Specimen Required Defines the optimal specimen. This field describes the type of specimen required to perform the test and the preferred volume to complete testing. The volume allows automated processing, fastest throughput and, when indicated, repeat or reflex testing.

All porphyrin tests on whole blood can be performed on 1 draw tube.

 

Container/Tube:

Preferred: Green top (sodium heparin)

Acceptable: Dark blue top (metal free heparin) or green top (lithium heparin)

Specimen Volume: Full tube

Collection Instructions:

1. Patient should abstain from alcohol for 24 hours.

2. Immediately place specimen on wet ice.

Forms

New York Clients-Informed consent is required. Please document on the request form or electronic order that a copy is on file. An Informed Consent for Genetic Testing (T576) is available in Special Instructions.

Specimen Minimum Volume The amount of sample necessary to provide a clinically relevant result as determined by the Laboratory.

3 mL

Reject Due To Identifies specimen types and conditions that may cause the specimen to be rejected

Hemolysis

Mild reject; Gross reject

Lipemia

NA

Icterus

NA

Other

NA

Specimen Stability Information Provides a description of the temperatures required to transport a specimen to the laboratory. Alternate acceptable temperature(s) are also included.

Specimen TypeTemperatureTime
Whole bloodRefrigerated7 days