CRY_S - Specimen: Cryoglobulin, Serum

Test Catalog

Test Name

Test ID: CRY_S    
Cryoglobulin, Serum

Testing Algorithm Delineates situations when tests are added to the initial order. This includes reflex and additional tests.

If cryoglobulin has a result other than negative, then iImmunofixation will be performed at an additional charge. Positive cryoglobulins of > or =0.1 mL of precipitate will be typed once.

Specimen Type Describes the specimen type validated for testing


Specimen Required Defines the optimal specimen. This field describes the type of specimen required to perform the test and the preferred volume to complete testing. The volume allows automated processing, fastest throughput and, when indicated, repeat or reflex testing.

Collection Container/Tube: Red top

Submission Container/Tube: Plastic vial

Specimen Volume: 5 mL

Collection Instructions:

1. Tube must remain at 37 degrees C.

2. Allow blood to clot at 37 degrees C.

3. Centrifuge at 37 degrees C. (Do not use a refrigerated centrifuge. If absolutely necessary, ambient temperature is acceptable.) It is very important that the specimen remain at 37 degrees C until after separation of serum from red cells.

4. Place serum into an appropriately labeled plastic vial.

Additional Information: Analysis cannot be performed with <3 mL of serum. Smaller volumes are insufficient to detect clinically important trace (mixed) cryoglobulins. Less than 3 mL will require draw of a new specimen.

Specimen Minimum Volume The amount of sample necessary to provide a clinically relevant result as determined by the Laboratory.

3 mL

Reject Due To Identifies specimen types and conditions that may cause the specimen to be rejected


Mild OK; Gross OK


Mild OK; Gross OK


Mild OK; Gross OK


Serum gel tube; plasma gel tube

Specimen Stability Information Provides a description of the temperatures required to transport a specimen to the laboratory. Alternate acceptable temperatures are also included.

Specimen TypeTemperatureTime
SerumRefrigerated (preferred)