MEX - Performance: Mexiletine, Serum

Test Catalog

Test Name

Test ID: MEX    
Mexiletine, Serum

Method Description Describes how the test is performed and provides a method-specific reference

Mexiletine is extracted with an organic solvent from serum at neutral or basic pH, but pH 10.4 is optimal for minimal interference from other drugs and maximal recovery. The organic extract is acidified and then evaporated under a stream of N(2). The residue is taken up in mobile phase and chromatographed by reverse-phase high-performance liquid chromatography (HPLC). Mexiletine is detected by absorbance at 210 nm and quantified by peak height ratios relative to an internal standard, p-chlorodisopyramide.(Mastropaolo W, Holmes DR, Osborn MJ, et al: Improved liquid-chromatographic determination of mexiletine, an antiarrhythmic drug, in plasma. Clin Chem 1984;30:319-322)

PDF Report Indicates whether the report includes an additional document with charts, images or other enriched information


Day(s) and Time(s) Test Performed Outlines the days and times the test is performed. This field reflects the day and time the sample must be in the testing laboratory to begin the testing process and includes any specimen preparation and processing time required before the test is performed. Some tests are listed as continuously performed, which means assays are performed several times during the day.

Monday, Wednesday, Friday; 9 a.m.

Analytic Time Defines the amount of time it takes the laboratory to setup and perform the test. This is defined in number of days. The shortest interval of time expressed is "same day/1 day," which means the results may be available the same day that the sample is received in the testing laboratory. One day means results are available 1 day after the sample is received in the laboratory.

Same day/1 day

Maximum Laboratory Time Defines the maximum time from specimen receipt at Mayo Medical Laboratories until the release of the test result

3 days

Specimen Retention Time Outlines the length of time after testing that a specimen is kept in the laboratory before it is discarded

14 days

Performing Laboratory Location The location of the laboratory that performs the test