ANCA - Overview: Cytoplasmic Neutrophil Antibodies, Serum

Test Catalog

Test Name

Test ID: ANCA    
Cytoplasmic Neutrophil Antibodies, Serum

Useful For Suggests clinical disorders or settings where the test may be helpful

Antineutrophil cytoplasmic antibodies (cANCA and pANCA):

-Evaluating patients suspected of having autoimmune vasculitis (both Wegener granulomatosis [WG] and microscopic polyangiitis)


cANCA titer:

-May be useful for monitoring treatment response in patients with WG (systemic or organ-limited disease); increasing titer suggests relapse of disease, while a decreasing titer suggests successful treatment


When used for diagnosis it is recommended that specific tests for proteinase 3 (PR3) ANCA and myeloperoxidase (MPO) ANCA be performed in addition to testing for cANCA and pANCA.(2) This panel of tests is available by ordering the VASC / Antineutrophil Cytoplasmic Antibodies Vasculitis Panel, Serum.

Method Name A short description of the method used to perform the test

Indirect Immunofluorescence

NY State Approved Indicates the status of NY State approval and if the test is orderable for NY State clients.


Reporting Name A shorter/abbreviated version of the Published Name for a test; an abbreviated test name

Cytoplasmic Neutrophilic Ab, S

Aliases Lists additional common names for a test, as an aid in searching

ACPA (Anti-Neutrophil Cytoplasmic Antibodies)
ANCA (Antineutrophil Cytoplasmic Antibodies)
ANCA (Wegener's)
Anti-Neutrophil Cytoplasmic Ab Test
Anti-Neutrophil Cytoplasmic Antibodies
Anticytoplasmic Antibody
Anticytoplasmic Autoantibodies
Antineutrophil Cytoplasmic Antibodies (ACPA)
Autoantibodies to Proteinase 3
c-ANCA (Anti-Neutrophil Cytoplasmic Antibodies)
cANCA (Antineutrophil Cytoplasmic Antibodies)
Cytoplasmic Antibody
Cytoplasmic Neutrophil Antibodies
MPO (Myeloperoxidase Antibodies)
Myeloperoxidase Antibodies (MPO)
Neutrophil Cytoplasmic Antibodies
pANCA (Perinuclear Antineutrophil Cytoplasmic Antibody)
Perinuclear anti-neutrophil cytoplasmic antibody (pANCA)
Perinuclear Antineutrophil Cytoplasmic Antibody (pANCA)
PR3 (Proteinase 3) Antineutrophil Cytoplasmic Antibodies
Proteinase 3 (PR3) Antineutrophil Cytoplasmic Antibodies
Wegener's Disease
Wegener's Granulomatosis