C5DCU - Overview: C5-DC Acylcarnitine, Quantitative, Urine

Test Catalog

Test Name

Test ID: C5DCU    
C5-DC Acylcarnitine, Quantitative, Urine

Useful For Suggests clinical disorders or settings where the test may be helpful

Evaluation of patients with an abnormal newborn screen showing elevations of C5-DC


Diagnosis of glutaric aciduria type 1 deficiency

Genetics Test Information Provides information that may help with selection of the correct genetic test or proper submission of the test request

Evaluation of patients with an abnormal newborn screen showing elevations of C5-DC. The results are not informative when patient is receiving L-carnitine supplements.


Elevated glutarylcarnitine (C5DC) in plasma or newborn screening blood spots is due to glutaric aciduria type 1 (GA-1), also known as glutaric acidemia type 1.


Urine C5DC is a biochemical marker of GA-1 that appears to be elevated even in low excretors, who are affected patients with normal levels of glutaric acid in urine.


If patient is receiving L-carnitine supplementation, the result of this urine acylcarnitine test will not be informative.

Special Instructions and Forms Library of PDFs including pertinent information and consent forms, specimen collection and preparation information, test algorithms, and other information pertinent to test

Method Name A short description of the method used to perform the test

Flow Injection Analysis-Tandem Mass Spectrometry (FIA-MS/MS)

NY State Approved Indicates the status of NY State approval and if the test is orderable for NY State clients.


Reporting Name A shorter or abbreviated version of the Published Name for a test; an abbreviated test name

C5-DC Acylcarnitine, QN, U

Aliases Lists additional common names for a test, as an aid in searching

Acylcarnitines, urine
GA 1
GCDH (Glutaryl-CoA Dehydrogenase) Deficiency
Glutaric Aciduria 1 (GA1) (GA 1)
Glutaric Aciduria Type 1
Glutaryl-CoA Dehydrogenase (GCDH) Deficiency