17PRN - Overview: Pregnenolone and 17-Hydroxypregnenolone

Test Catalog

Test Name

Test ID: 17PRN    
Pregnenolone and 17-Hydroxypregnenolone

Useful For Suggests clinical disorders or settings where the test may be helpful

An ancillary test for congenital adrenal hyperplasia (CAH), particularly in situations in which a diagnosis of 21-hydroxylase and 11-hydroxylase deficiency have been ruled out.

 

Confirming a diagnosis of 3-beta-hydroxy dehydrogenase (3-beta-HSD) deficiency and 17-alpha-hydroxylase deficiency.

 

Analysis for 17-hydroxypregnenolone is also useful as part of a battery of tests to evaluate females with hirsutism or infertility. Both can result from adult-onset CAH.

Profile Information A profile is a group of laboratory tests that are ordered and performed together under a single Mayo Test ID. Profile information lists the test performed, inclusive of the test fee, when a profile is ordered and includes reporting names and individual availability.

Test IDReporting NameAvailable SeparatelyAlways Performed
PREGNPregnenolone, SYesYes
17OHP17-Hydroxypregnenolone, SYesYes

Testing Algorithm Delineates situations when tests are added to the initial order. This includes reflex and additional tests.

See Steroid Pathways in Special Instructions.

Special Instructions and Forms Library of PDFs including pertinent information and consent forms, specimen collection and preparation information, test algorithms, and other information pertinent to test

Method Name A short description of the method used to perform the test

Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)

NY State Approved Indicates the status of NY State approval and if the test is orderable for NY State clients.

Yes

Reporting Name A shorter or abbreviated version of the Published Name for a test; an abbreviated test name

Pregnenolone and 17-OH Pregnenolone

Aliases Lists additional common names for a test, as an aid in searching

17-Hydroxypregnenolone