HTR2 - Overview: Serotonin Receptor Genotype (HTR2A and HTR2C)

Test Catalog

Test Name

Test ID: HTR2    
Serotonin Receptor Genotype (HTR2A and HTR2C)

Useful For Suggests clinical disorders or settings where the test may be helpful

Guiding treatment choice of a selective serotonin reuptake inhibitor (SSRI) or non-SSRI antidepressant


Guiding treatment choice in individuals who have a drug-metabolizer phenotype discordant with CYP450 genotypes


Identifying patients who may benefit from treatment with the antipsychotic drug clozapine and aripiprazole


Identifying those patients at risk of excessive weight gain when receiving antipsychotic medications

Testing Algorithm Delineates situations when tests are added to the initial order. This includes reflex and additional tests.


Special Instructions and Forms Library of PDFs including pertinent information and consent forms, specimen collection and preparation information, test algorithms, and other information pertinent to test

Method Name A short description of the method used to perform the test

Polymerase Chain Reaction (PCR) with Allele-Specific Primer Extension (ASPE)

NY State Approved Indicates the status of NY State approval and if the test is orderable for NY State clients.


Reporting Name A shorter/abbreviated version of the Published Name for a test; an abbreviated test name

Serotonin Receptor 2A/2C Genotype

Aliases Lists additional common names for a test, as an aid in searching

Serotonin Receptor HTR
Type 2 Serotonin Receptor 5HT