COMT - Overview: Catechol-O-Methyltransferase (COMT) Genotype

Test Catalog

Test Name

Test ID: COMT    
Catechol-O-Methyltransferase (COMT) Genotype

Useful For Suggests clinical disorders or settings where the test may be helpful

Early identification of patients who may show cognitive improvement with treatment for schizophrenia, this is associated with the COMT*2/ COMT*2 genotype


Investigation of inhibitor dosing for decreasing L-DOPA metabolism


Research use for assessing estrogen metabolism

Testing Algorithm Delineates situations when tests are added to the initial order. This includes reflex and additional tests.


Special Instructions and Forms Library of PDFs including pertinent information and consent forms, specimen collection and preparation information, test algorithms, and other information pertinent to test

Method Name A short description of the method used to perform the test

Polymerase Chain Reaction (PCR) with Allele-Specific Primer Extension (ASPE)

NY State Approved Indicates the status of NY State approval and if the test is orderable for NY State clients.


Reporting Name A shorter/abbreviated version of the Published Name for a test; an abbreviated test name

Catechol Methyltransferase Genotype

Aliases Lists additional common names for a test, as an aid in searching

Catechol O-methyltransferase