LUNGP - Overview: Lung Cancer-Targeted Gene Panel, Tumor

Test Catalog

Test Name

Test ID: LUNGP    
Lung Cancer-Targeted Gene Panel, Tumor

Useful For Suggests clinical disorders or settings where the test may be helpful

Identifying lung tumors that may respond to targeted therapies by assessing multiple gene targets within the EGFR, BRAF, KRAS, HRAS, NRAS, ALK, ERBB2, and MET genes simultaneously

 

Diagnosis and management of patients with lung cancer

Genetics Test Information Provides information that may help with selection of the correct test or proper submission of the test request

This test uses targeted next-generation sequencing to evaluate for somatic mutations within the EGFR, BRAF, KRAS, HRAS, NRAS, ALK, ERBB2, and MET genes. See Targeted Gene Regions Interrogated by Lung Panel in Special Instructions for details regarding the targeted gene regions evaluated by this test.

 

Of note, this test is performed to evaluate for somatic mutations within solid tumor samples. This test is not intended for use for hematological malignancies. Additionally, this test does not assess for germline alterations within the genes listed.

Highlights

Evaluates formalin-fixed, paraffin-embedded tumor or cytology slides from patients with lung cancer for gene mutations to identify candidates for targeted therapy.

 

Current data suggests that the efficacy of EGFR-targeted therapies in patients with non-small cell lung cancer is limited to tumors with mutations in the EGFR gene.

 

This test identifies activating exon 14 splice site mutations in the MET gene.

Additional Tests Lists test(s) that are always performed, at an additional charge, with the initial test(s)

Test IDReporting NameAvailable SeparatelyAlways Performed
SLIRVSlide Review in MGNo, (Bill Only)Yes

Testing Algorithm Delineates situation(s) when tests are added to the initial order. This includes reflex and additional tests.

When this test is ordered, slide review will always be performed at an additional charge.

Special Instructions and Forms Describes specimen collection and preparation information, test algorithms, and other information pertinent to test. Also includes pertinent information and consent forms to be used when requesting a particular test

Method Name A short description of the method used to perform the test

Polymerase Chain Reaction (PCR)-Based Next-Generation Sequencing

(PCR is utilized pursuant to a license agreement with Roche Molecular Systems, Inc.)

NY State Approved Indicates the status of NY State approval and if the test is orderable for NY State clients.

Yes

Reporting Name A shorter/abbreviated version of the Published Name for a test; an abbreviated test name

Lung Cancer Panel, Tumor

Aliases Lists additional common names for a test, as an aid in searching

EGFR
BRAF
KRAS
HRAS
NRAS
ERBB2
MET
ALK
Lung cancer mutation
Lung cancer panel
Lung panel
Lung tumor panel
Tumor panel
Oncology panel
Next Gen Sequencing Test
NGS