BRAFB - Overview: Cell-Free DNA BRAF V600 Test, Blood

Test Catalog

Test Name

Test ID: BRAFB    
Cell-Free DNA BRAF V600 Test, Blood

Useful For Suggests clinical disorders or settings where the test may be helpful

An alternative to invasive tissue biopsies for the determination of BRAF V600E and V600 K mutations


Identification of patients with melanoma who are most likely to benefit from targeted therapies

Genetics Test Information Provides information that may help with selection of the correct genetic test or proper submission of the test request

This test evaluates cell-free DNA (cfDNA) in the peripheral blood for the presence of BRAF V600E or K mutations in patients with melanoma and can be used to determine if these patients are candidates for targeted therapies.


This test is not validated for serial monitoring of patients with malignant melanoma, nor should it be used for evaluating patients with other malignancies. This test is also not intended as a screening test to identify cancer.


Evaluates peripheral blood for BRAF mutations in cell-free DNA


Detection of BRAF mutations in melanoma patients as an alternative for BRAF analysis of tissue


Current data suggests that the efficacy of BRAF-targeted therapy and anti-MEK therapy in melanoma is limited to patients whose tumors harbor a V600E/K mutation

Method Name A short description of the method used to perform the test

Digital Droplet Polymerase Chain Reaction (PCR)

NY State Approved Indicates the status of NY State approval and if the test is orderable for NY State clients.


Reporting Name A shorter or abbreviated version of the Published Name for a test; an abbreviated test name

cfDNA BRAF V600 Test, Blood

Aliases Lists additional common names for a test, as an aid in searching

Cell free DNA
cell-free DNA
circulating tumor DNA
liquid biopsy
Circulating tumor cells