KSQNU - Overview: Keratan Sulfate Quantitative , Urine

Test Catalog

Test Name

Test ID: KSQNU    
Keratan Sulfate Quantitative , Urine

Useful For Suggests clinical disorders or settings where the test may be helpful

Monitoring the pharmacodynamic effects of enzyme replacement therapy for Morquio A (MPS IVA)

Highlights

Morquio syndrome (MPSIV) is caused by a deficiency in the keratan degradation pathway and consists of types A and B.

 

Individuals with Morquio syndrome excrete keratan sulfate in their urine.

 

Enzyme replacement therapy (ERT) is available for Morquio A.

 

Measuring keratan sulfate in the urine of Morquio A patients undergoing ERT can be an appropriate tool for monitoring the pharmacodynamic effects of treatment

Method Name A short description of the method used to perform the test

Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)

NY State Approved Indicates the status of NY State approval and if the test is orderable for NY State clients.

Conditional

Reporting Name A shorter/abbreviated version of the Published Name for a test; an abbreviated test name

Keratan Sulfate Quantitative, U

Aliases Lists additional common names for a test, as an aid in searching

Beta-Galactosidase Deficiency
Keratan Sulfate
MPS IVA
Morquio A
Morquio B
N-acetylgalactosamine-6-sulfate sulfatase