KSQNU - Overview: Keratan Sulfate Quantitative, Urine

Test Catalog

Test Name

Test ID: KSQNU    
Keratan Sulfate Quantitative, Urine

Useful For Suggests clinical disorders or settings where the test may be helpful

Monitoring the pharmacodynamic effects of enzyme replacement therapy for Morquio A (MPS IVA)

Highlights

Morquio syndrome (MPSIV) is caused by a deficiency in the keratan degradation pathway and consists of types A and B.

 

Individuals with Morquio syndrome excrete keratan sulfate in their urine.

 

Enzyme replacement therapy (ERT) is available for Morquio A.

 

Measuring keratan sulfate in the urine of Morquio A patients undergoing ERT can be an appropriate tool for monitoring the pharmacodynamic effects of treatment

Special Instructions and Forms Library of PDFs including pertinent information and consent forms, specimen collection and preparation information, test algorithms, and other information pertinent to test

Method Name A short description of the method used to perform the test

Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)

NY State Approved Indicates the status of NY State approval and if the test is orderable for NY State clients.

Conditional

Reporting Name A shorter or abbreviated version of the Published Name for a test; an abbreviated test name

Keratan Sulfate Quantitative, U

Aliases Lists additional common names for a test, as an aid in searching

Beta-Galactosidase Deficiency
Keratan Sulfate
MPS IVA
Morquio A
Morquio B
N-acetylgalactosamine-6-sulfate sulfatase