LPCBS - Overview: Lysophosphatidylcholines by LC MS/MS, Blood Spot

Test Catalog

Test Name

Test ID: LPCBS    
Lysophosphatidylcholines by LC MS/MS, Blood Spot

Useful For Suggests clinical disorders or settings where the test may be helpful

Second-tier newborn screen for X-linked adrenoleukodystrophy (X-ALD)

Genetics Test Information Provides information that may help with selection of the correct test or proper submission of the test request

This test is used as a second-tier newborn screen for X-linked adrenoleukodystrophy (X-ALD).

Highlights

Testing for C24:0 lysophosphatidylcholines (LPC) and C26:0 LPC can aid in the diagnosis of X-linked adrenoleukodystrophy (X-ALD) as well as other types of peroxisomal disorders.

 

Analysis of LPCs in a blood spot test is a useful second-tier newborn screen test for X-ALD.

Testing Algorithm Delineates situation(s) when tests are added to the initial order. This includes reflex and additional tests.

For more information, see the following documents in Special Instructions:

-Newborn Screening Act Sheet X-linked Adrenoleukodystrophy: Increased Very Long Chain Fatty Acids

-Newborn Screen Follow-up for X-linked Adrenoleukodystrophy

Special Instructions and Forms Describes specimen collection and preparation information, test algorithms, and other information pertinent to test. Also includes pertinent information and consent forms to be used when requesting a particular test

Method Name A short description of the method used to perform the test

Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)

NY State Approved Indicates the status of NY State approval and if the test is orderable for NY State clients.

Conditional

Reporting Name A shorter/abbreviated version of the Published Name for a test; an abbreviated test name

LysoPC by LC MS/MS, BS

Aliases Lists additional common names for a test, as an aid in searching

Adrenoleukodystrophy (ALD)
Adrenomyeloneuropathy
LDSBS
LSD Screen
LSDBS
Lysosomal Storage Disorder Screen
Peroxisomal biogenesis disorders
X-linked adrenoleukodystrophy (XALD)
Zellweger Spectrum Syndrome (ZSS)
Zellweger Syndrome