ADM13 - Overview: ADAMTS13 Activity and Inhibitor Profile

Test Catalog

Test Name

Test ID: ADM13    
ADAMTS13 Activity and Inhibitor Profile

Useful For Suggests clinical disorders or settings where the test may be helpful

Assisting with the diagnosis of congenital or acquired thrombotic thrombocytopenic purpura

Profile Information A profile is a group of laboratory tests that are ordered and performed together under a single Mayo Test ID. Profile information lists the test performed, inclusive of the test fee, when a profile is ordered and includes reporting names and individual availability.

Test IDReporting NameAvailable SeparatelyAlways Performed
ADMFXADAMTS13 Activity AssayNoYes
ADMINADAMTS13 InterpretationNoYes

Reflex Tests Lists tests that may or may not be performed, at an additional charge, depending on the result and interpretation of the initial tests

Test IDReporting NameAvailable SeparatelyAlways Performed
ADMISADAMTS13 Inhibitor ScreenNoNo
ADMBUADAMTS13 Inhibitor Bethesda TiterNoNo

Testing Algorithm Delineates situations when tests are added to the initial order. This includes reflex and additional tests.

Testing begins with ADAMTS13 activity assay to evaluate the percent activity. If the ADAMTS13 activity assay is <30%, an inhibitor screen will be performed to look for specific ADAMTS13 inhibition. If specific inhibition is apparent, the titer of the inhibitor will be determined.

Special Instructions and Forms Library of PDFs including pertinent information and consent forms, specimen collection and preparation information, test algorithms, and other information pertinent to test

Method Name A short description of the method used to perform the test

ADMFX: Fluorescence Resonance Energy Transfer (FRET)

ADMIS, ADMBU: Mixing Studies

NY State Approved Indicates the status of NY State approval and if the test is orderable for NY State clients.


Reporting Name A shorter or abbreviated version of the Published Name for a test; an abbreviated test name

ADAMTS13 Activity and Inhibitor Profile

Aliases Lists additional common names for a test, as an aid in searching

Protease Activity Inhibitor for TTP
von Willebrand Factor Cleaving Protease
Thrombotic Microangiopathy
VWF protease activity and inhibitor