SEQU - Overview: Sequential Maternal Screening, Part 1, Serum

Test Catalog

Test Name

Test ID: SEQU    
Sequential Maternal Screening, Part 1, Serum

Useful For Suggests clinical disorders or settings where the test may be helpful

Prenatal screening for Down syndrome and trisomy 18


Prenatal screening for neural tube defects (this is only applicable to Part 2 [second trimester] of the test)

Testing Algorithm Delineates situations when tests are added to the initial order. This includes reflex and additional tests.

Sequential maternal screening is a 2-part test, with first- and second-trimester components. It requires a nuchal translucency (NT) measurement and blood draw in the first trimester. If the result from Part 1 indicates a risk for Down syndrome that is higher than the screen cutoff, the screen is completed and a report is issued. If Part 1 results are negative, an additional blood draw in the second trimester is required (see SEQF / Sequential Maternal Screening, Part 2, Serum). If the second specimen is not received for sequential screening, the results are uninterpretable and no maternal risk will be provided.


The following are available in Special Instructions:

-Sequential Maternal Serum Screening Testing Process

-Prenatal Aneuploidy Screening and Diagnostic Testing Options Algorithm

Special Instructions and Forms Library of PDFs including pertinent information and consent forms, specimen collection and preparation information, test algorithms, and other information pertinent to test

Method Name A short description of the method used to perform the test

Two-Site Immunoenzymatic (Sandwich) Assay

NY State Approved Indicates the status of NY State approval and if the test is orderable for NY State clients.


Reporting Name A shorter/abbreviated version of the Published Name for a test; an abbreviated test name

Sequential Maternal Screen, Part 1

Aliases Lists additional common names for a test, as an aid in searching

Maternal Serum Sequential Screen
Sequential Screening
Serum Stepwise Sequential Screen
Stepwise Maternal Screen
Stepwise Sequential