PQNRU - Overview: Porphyrins, Quantitative, Random, Urine

Test Catalog

Test Name

Test ID: PQNRU    
Porphyrins, Quantitative, Random, Urine

Useful For Suggests clinical disorders or settings where the test may be helpful

Preferred test to begin assessment for congenital erythropoietic porphyria and porphyria cutanea tarda and during symptomatic periods for acute intermittent porphyria, hereditary coproporphyria, and variegate porphyria when specimen transport will not exceed 72 hours

Genetics Test Information Provides information that may help with selection of the correct genetic test or proper submission of the test request

This test is preferred test during symptomatic periods for acute intermittent porphyria (AIP), hereditary coproporphyria (HCP), and variegate porphyria (VP). The random urine collection for this test allows for the diagnosis to be established and treatment to be initiated quickly. However, this test should only be ordered when the specimen will be received at MML within 72 hours of collection. If it will be longer, PQNU / Porphyrins, Quantitative, 24 Hour, Urine should be ordered.


Testing includes porphobilinogen which is useful in the evaluation of the acute porphyrias.


This is the preferred test to begin assessment for congenital erythropoietic porphyria (CEP) and porphyria cutanea tarda (PCT).

Testing Algorithm Delineates situations when tests are added to the initial order. This includes reflex and additional tests.

The following algorithms are available in Special Instructions:

-Porphyria (Acute) Testing Algorithm

-Porphyria (Cutaneous) Testing Algorithm

Special Instructions and Forms Library of PDFs including pertinent information and consent forms, specimen collection and preparation information, test algorithms, and other information pertinent to test

Method Name A short description of the method used to perform the test

High-Performance Liquid Chromatography (HPLC) with Fluorometric Detection


Includes quantitation of coproporphyrins, uroporphyrins, and intermediate porphyrins (heptacarboxyl, hexacarboxyl, and pentacarboxyl).


Includes liquid chromatography-tandem mass spectrometry (LC-MS/MS) determination of porphobilinogen.

NY State Approved Indicates the status of NY State approval and if the test is orderable for NY State clients.


Reporting Name A shorter or abbreviated version of the Published Name for a test; an abbreviated test name

Porphyrins, QN, Random, U

Aliases Lists additional common names for a test, as an aid in searching

Acute Intermittent Porphyria (AIP)
Congenital Erythropoietic Porphyria (CEP)
Hereditary Coproporphyria (HCP)
PBG (Porphobilinogen)
Porphyria Cutanea Tarda (PCT)
Variegate Porphyria (VP)