MGA1 - Overview: Myasthenia Gravis (MG) Evaluation, Adult

Test Catalog

Test Name

Test ID: MGA1    
Myasthenia Gravis (MG) Evaluation, Adult

Useful For Suggests clinical disorders or settings where the test may be helpful

Initial evaluation of patients aged 20 or older with symptoms and signs of acquired myasthenia gravis (MG)

 

Bone marrow transplant recipients with suspected graft-versus-host disease, particularly if weakness has appeared

 

Confirming that a recently acquired neurological disorder has an autoimmune basis (eg, MG)

 

Providing a quantitative baseline for future comparisons in monitoring a patient's clinical course and the response to immunomodulatory treatment

 

Raising likelihood of neoplasia

Profile Information A profile is a group of laboratory tests that are ordered and performed together under a single Mayo Test ID. Profile information lists the test performed, inclusive of the test fee, when a profile is ordered and includes reporting names and individual availability.

Test IDReporting NameAvailable SeparatelyAlways Performed
MGEAIMG Adult Interpretation, SNoYes
ARBIACh Receptor (Muscle) Binding AbYesYes
ARMOACh Receptor (Muscle) Modulating AbNoYes
STRStriational (Striated Muscle) Ab, SYesYes

Reflex Tests Lists test(s) that may or may not be performed, at an additional charge, depending on the result and interpretation of the initial test(s)

Test IDReporting NameAvailable SeparatelyAlways Performed
GD65SGAD65 Ab Assay, SYesNo
CRMWSCRMP-5-IgG Western Blot, SYesNo
GANGAChR Ganglionic Neuronal Ab, SNoNo
VGKCNeuronal (V-G) K+ Channel Ab, SNoNo

Testing Algorithm Delineates situation(s) when tests are added to the initial order. This includes reflex and additional tests.

If acetylcholine receptor (AChR) modulating antibodies are > or =90% and striational antibodies are > or =1:120, then AChR ganglionic neuronal autoantibody, glutamic acid decarboxylase autoantibody, neuronal voltage-gated potassium channel autoantibody, and CRMP-5-IgG Western blot will be performed at an additional charge.

 

See Myasthenia Gravis: Adult Diagnostic Algorithm in Special Instructions.

Special Instructions and Forms Describes specimen collection and preparation information, test algorithms, and other information pertinent to test. Also includes pertinent information and consent forms to be used when requesting a particular test

Method Name A short description of the method used to perform the test

ARBI, ARMO, GANG, GD65S, VGKC: Radioimmunoassay (RIA)

STR: Enzyme Immunoassay (EIA)

NY State Approved Indicates the status of NY State approval and if the test is orderable for NY State clients.

Yes

Reporting Name A shorter/abbreviated version of the Published Name for a test; an abbreviated test name

MG Evaluation, Adult

Aliases Lists additional common names for a test, as an aid in searching

Acetylcholine Receptor (Muscle AChR) Antibodies
Ach Receptor Ab
ACh Receptor Blocking Ab
AChR (Acetylcholine Receptor)
Anti-Skeletal Muscle Antibodies
Binding, Blocking, and Modulating Abs
Blocking Ab
GAD65 (Glutamic Acid Decarboxylase)
Glutamate Decarboxylase Antibodies (GAD65)
Muscle End-Plate Antibodies
Myasthenia Gravis Antibodies
Myoid Antibody
Neuronal Potassium Channel Ab
Potassium Channel Antibodies (specify)
Striational (Striated Muscle) Antibodies
VGKC
VGPC
Voltage-Gated Potassium Channel Ab