MGMT - Overview: MGMT Promoter Methylation, Tumor

Test Catalog

Test Name

Test ID: MGMT    
MGMT Promoter Methylation, Tumor

Useful For Suggests clinical disorders or settings where the test may be helpful

Prognostication of newly diagnosed glioblastomas


Identifying newly diagnosed glioblastomas that may respond to alkylating chemotherapy (ie, temozolomide)


Guidance for therapy decision making for newly diagnosed glioblastomas in elderly patients (older than 60-65 years)


MGMT promoter methylation status has prognostic and predictive value for glioblastoma patients

Additional Tests Lists test(s) that are always performed, at an additional charge, with the initial test(s)

Test IDReporting NameAvailable SeparatelyAlways Performed
SLIRVSlide Review in MGNoYes

Testing Algorithm Delineates situation(s) when tests are added to the initial order. This includes reflex and additional tests.

Slide review will always be performed prior to testing.

Method Name A short description of the method used to perform the test

Methylation-Specific Polymerase Chain Reaction (PCR) Analysis

(PCR is utilized pursuant to a license agreement with Roche Molecular Systems, Inc.)

NY State Approved Indicates the status of NY State approval and if the test is orderable for NY State clients.


Reporting Name A shorter/abbreviated version of the Published Name for a test; an abbreviated test name

MGMT Promoter Methylation, Tumor