Test Catalog

Test Name

Test ID: FLG    
FLG Gene, Mutation Analysis

Useful For Suggests clinical disorders or settings where the test may be helpful

Genetic diagnosis of ichthyosis vulgaris for clinical management, risk assessment for atopic diseases and atopic disease-associated asthma, and genetic counseling for family members

Genetics Test Information Provides information that may help with selection of the correct genetic test or proper submission of the test request

This test identifies 2 common mutations (R501X and 2282del4) in the FLG gene that cause ichthyosis vulgaris.

Reflex Tests Lists tests that may or may not be performed, at an additional charge, depending on the result and interpretation of the initial tests.

Test IDReporting NameAvailable SeparatelyAlways Performed
CULFBFibroblast Culture for Genetic TestYesNo

Testing Algorithm Delineates situations when tests are added to the initial order. This includes reflex and additional tests.

If skin biopsy is received, fibroblast culture for genetic test will be added and charged separately.

Special Instructions Library of PDFs including pertinent information and forms related to the test

Method Name A short description of the method used to perform the test

Polymerase Chain Reaction (PCR) Followed by DNA Sequence Analysis

NY State Available Indicates the status of NY State approval and if the test is orderable for NY State clients.

Yes

Reporting Name Lists a shorter or abbreviated version of the Published Name for a test

FLG Gene, Mutation Analysis

Aliases Lists additional common names for a test, as an aid in searching

Atopic dermatitis
Atopic disease
Filaggrin
Filament aggregating protein
FLGA
FLG
Ichthyosis simplex
Profilagrin
Ichthyosis vulgaris