EGFRR - Overview: Lung Cancer, EGFR with ALK Reflex, Tumor

Test Catalog

Test Name

Test ID: EGFRR    
Lung Cancer, EGFR with ALK Reflex, Tumor

Useful For Suggests clinical disorders or settings where the test may be helpful

Identifying non-small cell lung cancers that may benefit from treatment with epidermal growth factor receptor-tyrosine kinase or anaplastic lymphoma kinase inhibitors

Reflex Tests Lists test(s) that may or may not be performed, at an additional charge, depending on the result and interpretation of the initial test(s)

Test IDReporting NameAvailable SeparatelyAlways Performed
LCAFALK (2p23), Lung Cancer, FISH, TsYesNo

Additional Tests Lists test(s) that are always performed, at an additional charge, with the initial test(s)

Test IDReporting NameAvailable SeparatelyAlways Performed
SLIRVSlide Review in MGNo, (Bill Only)Yes

Testing Algorithm Delineates situation(s) when tests are added to the initial order. This includes reflex and additional tests.

When this test is ordered, EGFR and LCAF testing will always be ordered. The EGFR Gene, Mutation Analysis, 29 Mutation Panel, Tumor, will always be performed. All specimens without an EGFR mutation will be automatically reflexed to LCAF / ALK (2p23), Lung Cancer, FISH Tissue. Specimens with an identified EGFR mutation will result in cancellation of the LCAF test.

 

When this test is ordered, slide review will always be performed at an additional charge.

Method Name A short description of the method used to perform the test

Polymerase Chain Reaction (PCR) and Fluorescence In Situ Hybridization (FISH)

(PCR is utilized pursuant to a license agreement with Roche Molecular Systems, Inc.)

NY State Approved Indicates the status of NY State approval and if the test is orderable for NY State clients.

Yes

Reporting Name A shorter/abbreviated version of the Published Name for a test; an abbreviated test name

Lung Cancer, EGFR with ALK Reflex

Aliases Lists additional common names for a test, as an aid in searching

2p23
ALK
ALK Fish
ALK-EML4
EGFR
EGFR-TKI
EGFR-tyrosine kinase inhibitor
Epidermal growth factor receptor
Erlotinib
Gefitinib
Lung carcinoma
Non small cell lung cancer
Non-small cell lung cancer
NSCLC
EGFRX
T790M