TLYMF - Overview: T-Cell Lymphoma, FISH, Tissue

Test Catalog

Test Name

Test ID: TLYMF    
T-Cell Lymphoma, FISH, Tissue

Useful For Suggests clinical disorders or settings where the test may be helpful

Detecting a neoplastic clone associated with the common chromosome abnormalities seen in patients with various T-cell lymphomas


Tracking known chromosome abnormalities and response to therapy in patients with T-cell lymphomas

Reflex Tests Lists tests that may or may not be performed, at an additional charge, depending on the result and interpretation of the initial tests

Test IDReporting NameAvailable SeparatelyAlways Performed
_PBCTProbe, +2No, No (Bill Only)No
_PADDProbe, +1No, No (Bill Only)No
_PB02Probe, +2No, No (Bill Only)No
_PB03Probe, +3No, No (Bill Only)No
_IL25Interphases, <25No, No (Bill Only)No
_I099Interphases, 25-99No, No (Bill Only)No
_I300Interphases, >=100 No, No (Bill Only)No

Testing Algorithm Delineates situations when tests are added to the initial order. This includes reflex and additional tests.

This test does not include a pathology consultation. If a pathology consultation is requested, PATHC / Pathology Consultation should be ordered and the appropriate FISH test will be ordered and performed at an additional charge. Mayo Hematopathology Consultants are involved in both the pre-analytic (tissue adequacy and probe selection, when applicable) and post-analytic (interpretation of FISH results in context of specific case, when applicable) phases.


This test includes a charge for application of the first probe set (2 FISH probes) and professional interpretation of results.


Additional charges will be incurred for all reflex probes performed. Analysis charges will be incurred based on the number of cells analyzed per probe set. If no cells are available for analysis, no analysis charges will be incurred.


Depending on the lymphoma subtype suspected, the most appropriate probes to order are listed in the Clinical Information.


If the patient is being tracked for known abnormalities, indicate which probes should be used.


Panel includes testing for the following abnormalities using the probes listed:

14q32.1 rearrangement, TCL1A

-7/7q-/i(7q), D7S486/D7Z1

+8, D8Z2/MYC

2p23.2 rearrangement, ALK


This assay detects chromosome abnormalities observed in paraffin-embedded tissue samples of patients with T-cell lymphoma. For testing the blood and bone marrow from patients with T-cell lymphoma, see TLPF / T-Cell Lymphoma, FISH, Blood or Bone Marrow.

Method Name A short description of the method used to perform the test

Fluorescence In Situ Hybridization (FISH)

NY State Approved Indicates the status of NY State approval and if the test is orderable for NY State clients.


Reporting Name A shorter or abbreviated version of the Published Name for a test; an abbreviated test name

T-cell Lymphoma, FISH, Ts

Aliases Lists additional common names for a test, as an aid in searching

ALK (2p23) rearrangement
+8 (trisomy 8)
Hepatosplenic T-Cell Lymphoma
inv(14) - inversion 14
Iso(7q) - isochromosome 7q
T-cell Prolymphocytic Leukemia (T-PLL)
TCL1A (14q32) rearrangement