PPFWE - Overview: Protoporphyrins, Fractionation, Washed Erythrocytes

Test Catalog

Test Name

Test ID: PPFWE    
Protoporphyrins, Fractionation, Washed Erythrocytes

Useful For Suggests clinical disorders or settings where the test may be helpful

Preferred test for analysis of erythrocyte protoporphyrin fractions


Preferred test for evaluating patients with possible diagnoses of erythropoietic protoporphyria and X-linked dominant protoporphyria


Establishing a biochemical diagnosis of erythropoietic protoporphyria, and X-linked dominant protoporphyria

Testing Algorithm Delineates situations when tests are added to the initial order. This includes reflex and additional tests.

This test should not be ordered in conjunction with PEWE / Porphyrins Evaluation, Washed Erythrocytes.


The following algorithms are available in Special Instructions:

-Porphyria (Acute) Testing Algorithm

-Porphyria (Cutaneous) Testing Algorithm

Special Instructions and Forms Library of PDFs including pertinent information and consent forms, specimen collection and preparation information, test algorithms, and other information pertinent to test

Method Name A short description of the method used to perform the test

High-Performance Liquid Chromatography (HPLC) with Fluorescence Detection

NY State Approved Indicates the status of NY State approval and if the test is orderable for NY State clients.


Reporting Name A shorter/abbreviated version of the Published Name for a test; an abbreviated test name

Protoporphyrins, Fractionation, RBC

Aliases Lists additional common names for a test, as an aid in searching

EPP (Erythropoietic Protoporphyria)
Erythropoietic Protoporphyria
Free Protoporphyrin
Zinc Protoporphyrin
X-linked Dominant Protoporphyria (XLDPP or XDP)