FSOMA - Clinical: Somatostatin

Test Catalog

Test Name

Test ID: FSOMA    

Clinical Information Discusses physiology, pathophysiology, and general clinical aspects, as they relate to a laboratory test

Somatostatin is a cyclic peptide originally isolated from sheep hypothalami

and shown to inhibit the release of Growth Hormone. Somatostatin is present

primarily in three main forms: a 14 amino acid peptide, a 28 amino acid peptide

(Big Somatostatin), and a 12,000 molecular weight Pro-Somatostatin. This

assay measures only the 14 amino acid form of Somatostatin. All three forms

of Somatostatin have similar biological properties and overall potencies.

Somatostatin is a physiological regulator of islet cell and gastrointestinal functions,

and is a suppressor of many pituitary hormones including Growth Hormone, Prolactin,

and Thyrotropin (TSH). Somatostatin levels are often elevated in diabetics, but the

levels return to normal upon correction of the hormonal and metabolic deficiencies

present. In many cases of APUDomas including VIPoma, Insulinoma, Glucagonoma,

and Gastrinoma, elevated levels of Somatostatin are found. 

Reference Values Describes reference intervals and additional information for interpretation of test results. May include intervals based on age and sex when appropriate. Intervals are Mayo-derived, unless otherwise designated. If an interpretive report is provided, the reference value field will state this.

Up to 25 pg/ml


This test was developed and its performance characteristics

determined by Inter Science Institute. It has not been cleared or

approved by the US Food and Drug Administration. The FDA

has determined that such clearance or approval is not necessary.