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Test ID: NMRLS
LDL and HDL Particle Concentration NMR with Lipids, Plasma

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Reference Values Describes reference intervals and additional information for interpretation of test results. May include intervals based on age and sex when appropriate. Intervals are Mayo-derived, unless otherwise designated. If an interpretive report is provided, the reference value field will state this.

The National Cholesterol Education Program (NCEP) has set the following guidelines for lipids (total cholesterol; triglycerides; HDL; and LDL cholesterol) in adults ages 18 and up:

TOTAL CHOLESTEROL

Desirable: <200 mg/dL

Borderline high: 200-239 mg/dL

High: > or =240 mg/dL

 

TRIGLYCERIDES

Normal: <150 mg/dL

Borderline high: 150-199 mg/dL

High: 200-499 mg/dL

Very high: > or =500 mg/dL

 

HDL CHOLESTEROL

Low: <40 mg/dL

Normal: 40-59 mg/dL

High: > or =60 mg/dL

 

LDL CHOLESTEROL

Optimal: <100 mg/dL

Near optimal: 100-129 mg/dL

Borderline high: 130-159 mg/dL

High: 160-189 mg/dL

Very high: > or =190 mg/dL

 

NON-HDL CHOLESTEROL

Desirable: <130 mg/dL

Borderline high: 130-159 mg/dL

High: 160-189 mg/dL

Very high: > or =190 mg/dL

 

The National Cholesterol Education Program (NCEP) and National Health and Nutrition Examination Survey (NHANES) have set the following guidelines for lipids (total cholesterol, triglycerides, HDL, and LDL cholesterol) in children ages 2-17:

TOTAL CHOLESTEROL

Desirable: <170 mg/dL

Borderline high: 170-199 mg/dL

High: > or =200 mg/dL

 

TRIGLYCERIDES

Normal: <90 mg/dL

Borderline high: 90-129 mg/dL

High: > or =130 mg/dL

 

HDL CHOLESTEROL

Low: <40 mg/dL

Normal: 40-59 mg/dL

Desirable: > or =60 mg/dL

 

LDL CHOLESTEROL

Desirable: <110 mg/dL

Borderline high: 110-129 mg/dL

High: > or =130 mg/dL

 

NON-HDL CHOLESTEROL

Desirable: <130 mg/dL

Borderline high: 130-159 mg/dL

High: 160-189 mg/dL

Very high: > or =190 mg/dL

 

NMR LIPOPROTEIN PARTICLES TOTAL LDL PARTICLE CONCENTRATION

< or =15 years: not established

Adult (> or =16 years):

<1,000 nmol/L (optimal)

1,000-1,299 nmol/L (near or above optimal)

1,300-1,599 nmol/L (borderline high)

1,600-2,000 nmol/L (high)

>2,000 nmol/L (very high)

 

SMALL LDL PARTICLE CONCENTRATION

< or =15 years: not established

Adult (> or =16 years):

<117 nmol/L (optimal)

117-526 nmol/L (intermediate)

527-839 nmol/L (borderline high)

>839 nmol/L (high)

 

TOTAL HDL PARTICLE CONCENTRATION

< or =15 years: not established

Adults (> or =16 years):

<26.7 mcmol/L (low)

26.7-34.9 mcmol/L (intermediate)

>34.9 mcmol/L (optimal)

 

LARGE HDL PARTICLE CONCENTRATION

< or =15 years: not established

Adults (> or =16 years):

<3.1 mcmol/L (low)

3.1-7.3 mcmol/L (intermediate)

>7.3 mcmol/L (optimal)

 

Small LDL, Total HDL and Large HDL Particle Concentrations were validated by LipoScience and the CVLM laboratory at the Mayo Clinic. NMR spectra are generated at Mayo Clinic, 200 First St., Rochester, MN 55905 and results calculated by Liposcience, Inc., 2500 Sumner Boulevard, Raleigh NC 27616.



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