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Test ID: IGF1I
Insulin-Like Growth Factor 1, Serum

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Reference Values Describes reference intervals and additional information for interpretation of test results. May include intervals based on age and sex when appropriate. Intervals are Mayo-derived, unless otherwise designated. If an interpretive report is provided, the reference value field will state this.

Males:

Age

ng/mL

0.1 Percentile (ng/mL)

0-11 months

15-150

3

1 year

18-179

4

2 years

22-204

5

3 years

25-224

6

4 years

28-241

8

5 years

32-259

9

6 years

36-281

11

7 years

42-311

13

8 years

49-351

16

9 years

58-401

19

10 years

70-458

24

11 years

82-516

29

12 years

93-567

35

13 years

103-603

41

14 years

111-620

46

15 years

115-618

50

16 years

115-598

52

17 years

113-566

54

18 years

109-527

 

19 years

104-484

 

20 years

98-443

 

21-25 years

83-344

 

26-30 years

75-275

 

31-35 years

71-241

 

36-40 years

69-226

 

41-45 years

64-210

 

46-50 years

59-201

 

51-55 years

56-201

 

56-60 years

51-194

 

61-65 years

47-191

 

66-70 years

46-195

 

71-75 years

42-187

 

76-80 years

39-184

 

80-85 years

37-182

 

85-90 years

35-182

 

 

Females:

Age

ng/mL

0.1 Percentile (ng/mL)

0-11 months

18-146

5

1 year

20-159

6

2 years

23-177

7

3 years

27-198

8

4 years

32-223

10

5 years

36-246

12

6 years

41-269

15

7 years

48-299

17

8 years

56-339

21

9 years

68-396

26

10 years

83-465

32

11 years

99-537

40

12 years

115-598

48

13 years

126-637

56

14 years

133-647

62

15 years

134-631

65

16 years

130-595

66

17 years

123-546

64

18 years

114-493

 

19 years

105-441

 

20 years

97-398

 

21-25 years

84-323

 

26-30 years

77-271

 

31-35 years

73-244

 

36-40 years

68-225

 

41-45 years

62-205

 

46-50 years

56-194

 

51-55 years

53-191

 

56-60 years

45-173

 

61-65 years

41-168

 

66-70 years

39-168

 

71-75 years

36-166

 

76-80 years

35-168

 

80-85 years

35-179

 

85-90 years

33-179

 

Reference values have not been established for patients that are >90 years of age.

 

IGF-1 reference values according to Tanner stages I-V(2)

Males

Stage I: 83-255 ng/mL

Stage II: 114-440 ng/mL

Stage III: 236-516 ng/mL

Stage IV: 218-580 ng/mL

Stage V: 229-522 ng/mL

Females

Stage I: 90-324 ng/mL

Stage II: 104-456 ng/mL

Stage III: 249-519 ng/mL

Stage IV: 238-574 ng/mL

Stage V: 187-509 ng/mL

 

Note: Puberty onset, ie the transition from Tanner stage 1 (prepubertal) to Tanner stage 2 (early pubertal), occurs for girls at a median age of 10.5 (+/-2) years and for boys at a median age of 11.5 (+/-2) years. There is evidence that it may occur up to 1 year earlier in obese girls and in African-American girls. By contrast, for boys there is no definite proven relationship between puberty onset and body weight or ethnic origin. Progression through Tanner stages is variable. Tanner stage 5 (young adult) should be reached by age 18.



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