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Test ID: TGAB    
Thyroglobulin Antibody, Serum

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Method Description Describes how the test is performed and provides a method-specific reference

Testing is performed on a Roche Cobas instrument. The Roche Thyroglobulin Antibody assay (anti-Tg) is a competitive assay using electrochemiluminescence detection. Patient specimen is incubated with biotinylated Tg and antibodies in the sample bind to the antigen in the reagent. Anti-Tg antibodies labeled with ruthenium complex and streptaviadin-coated microparticles are added and the immunocomplex produced becomes bound to the solid phase by interaction of biotin and streptavidin. The reaction mixture is aspirated into the measuring cell where the microparticles are magnetically captured onto the surface of the electrode. Unbound substances are then removed with ProCell. Application of a voltage to the electrode induces the electrochemiluminescent emission. This signal is measured against a calibration curve to determine patient results.(Package insert: Roche Cobas. Roche Diagnostics, Indianapolis, IN 2010)

Day(s) and Time(s) Test Performed Outlines the days and times the test is performed. This field reflects the day and time the sample must be in the testing laboratory to begin the testing process and includes any specimen preparation and processing time required before the test is performed. Some tests are listed as continuously performed, which means assays are performed several times during the day.

Monday through Friday 5 a.m. – 12 a.m., Saturday 6 a.m. – 6 p.m.

Analytic Time Defines the amount of time it takes the laboratory to setup and perform the test. This is defined in number of days. The shortest interval of time expressed is "same day/1 day," which means the results may be available the same day that the sample is received in the testing laboratory. One day means results are available 1 day after the sample is received in the laboratory.

Same day/1 day

Maximum Laboratory Time Defines the maximum time from specimen receipt at Mayo Medical Laboratories until the release of the test result

3 days

Specimen Retention Time Outlines the length of time after testing that a specimen is kept in the laboratory before it is discarded

3 months

Performing Laboratory Location The location of the laboratory that performs the test

Rochester