Thyroglobulin Antibody, Serum
Method Description Describes how the test is performed and provides a method-specific reference
Testing is performed on a Roche Cobas instrument. The Roche Thyroglobulin Antibody assay (anti-Tg) is a competitive assay using electrochemiluminescence detection. Patient specimen is incubated with biotinylated Tg and antibodies in the sample bind to the antigen in the reagent. Anti-Tg antibodies labeled with ruthenium complex and streptaviadin-coated microparticles are added and the immunocomplex produced becomes bound to the solid phase by interaction of biotin and streptavidin. The reaction mixture is aspirated into the measuring cell where the microparticles are magnetically captured onto the surface of the electrode. Unbound substances are then removed with ProCell. Application of a voltage to the electrode induces the electrochemiluminescent emission. This signal is measured against a calibration curve to determine patient results.(Package insert: Roche Cobas. Roche Diagnostics, Indianapolis, IN 2010)
PDF Report Indicates whether the report includes an additional document with charts, images or other enriched information
Day(s) and Time(s) Test Performed Outlines the days and times the test is performed. This field reflects the day and time the sample must be in the testing laboratory to begin the testing process and includes any specimen preparation and processing time required before the test is performed. Some tests are listed as continuously performed, which means assays are performed several times during the day.
Monday through Friday 5 a.m. – 12 a.m., Saturday 6 a.m. – 6 p.m.