Diabetes Mellitus Type 1 Evaluation
Method Description Describes how the test is performed and provides a method-specific reference
(125)I-labeled recombinant human antigen (glutamic acid decarboxylase 65, islet antigen 2, or insulin) is added to the test serum. If antibody is present, it forms a soluble complex with the (125)I-labeled antigen. Subsequent addition of goat antihuman IgG and IgM precipitates the complex. The amount of radioactivity in the precipitate is proportional to the level of antibody in the serum.(Masuda M, Powell M, Chen S, et al: Autoantibodies to IA-2 in insulin-dependent diabetes mellitus. Measurements with a new immunoprecipitation assay. Clin Chim Acta 2000;291:53-66)
PDF Report Indicates whether the report includes an additional document with charts, images or other enriched information
Day(s) and Time(s) Test Performed Outlines the days and times the test is performed. This field reflects the day and time the sample must be in the testing laboratory to begin the testing process and includes any specimen preparation and processing time required before the test is performed. Some tests are listed as continuously performed, which means assays are performed several times during the day.
Monday through Thursday, Sunday; 10 p.m.
GAD65 antibody: Monday through Thursday, Sunday; 8 a.m.
Insulin antibodies: Monday, Thursday; 10 p.m.
IA-2 antibody: Tuesday, Friday; 10 p.m.