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Test ID: TCP    
T-Cell Subsets, Naive, Memory and Activated

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NY State Approved Indicates the status of NY State approval and if the test is orderable for NY State clients.

No

Useful For Suggests clinical disorders or settings where the test may be helpful

Determining the presence of naive, memory, and activated T cells in various clinical contexts including autoimmune diseases, immunodeficiency states, T-cell recovery posthematopoietic stem cell transplant, DiGeorge syndrome, and as a measure for T-cell immune competence

 

Naive T-cells results can be used a surrogate marker for thymic-derived T-cell reconstitution, when used in conjunction with assessment of T-cell receptor excision circles (TREC / T-Cell Receptor Excision Circles [TREC] Analysis for Immune Reconstitution)

 

Assessing a patient's relative risk for infections

 

Evaluation of patients with cellular or combined primary immunodeficiencies

 

Evaluation of T-cell reconstitution after hematopoietic stem cell transplant, chemotherapy, biological therapy, immunosuppression or immunomodulator therapy

 

Evaluation of patients with autoimmune diseases

 

Evaluation of HIV-positive patients for naive and memory subsets

 

Evaluation of T-cell immune competence (presence of memory and activated T cells) in patients with recurrent infections

Method Name A short description of the method used to perform the test

Flow Cytometry

Reporting Name A shorter/abbreviated version of the Published Name for a test; an abbreviated test name

T Cell Phenotyping, Advanced

Aliases Lists additional common names for a test, as an aid in searching

Activated T cells
CD27+ T cells
CD28+ T cells
CD4+ T cells
CD45RA
CD45RO
CD62L+ T cells
CD8+ T cells
Central memory T cells
DiGeorge syndrome T cells
Effector memory T cells
HIV T cells
Immune competence T cells
Immune reconstitution T cells
Infection T cells
Intestinal lymphangiectasia T cells
Memory
MHC class II-positive T cells
Naive
T-cell depletion T cells