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Test ID: MPSEX    
Monoclonal Protein Study, Expanded Panel, Serum

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NY State Approved Indicates the status of NY State approval and if the test is orderable for NY State clients.


Useful For Suggests clinical disorders or settings where the test may be helpful

Diagnosis of monoclonal gammopathies  


Eliminating the need for urine monoclonal studies as a part of initial diagnostic studies (ie, rule-out monoclonal gammopathy)


Assessing risk of progression from monoclonal gammopathy of undetermined significance to multiple myeloma

Profile Information A profile is a group of laboratory tests that are ordered and performed together under a single Mayo Test ID. Profile information lists the test performed, inclusive of the test fee, when a profile is ordered and includes reporting names and individual availability.

Test IDReporting NameAvailable SeparatelyAlways Performed
TPETotal ProteinYes, (order TP)Yes
ELPProtein ElectrophoresisNoYes
KFLCKappa Free Light Chain, SNoYes
LFLCLambda Free Light Chain, SNoYes
KLRKappa/Lambda FLC RatioNoYes

Testing Algorithm Delineates situation(s) when tests are added to the initial order. This includes reflex and additional tests.

Includes total protein, serum protein electrophoresis (SPEP), heavy chain and light chain typing (kappa and lambda).

Method Name A short description of the method used to perform the test

TPE: Biuret

ELP: Agarose Gel Electrophoresis

IMFX: Immunofixation

KFLC, LFLC, KLR: Nephelometry

Reporting Name A shorter/abbreviated version of the Published Name for a test; an abbreviated test name

MPSS Expanded Panel, S

Aliases Lists additional common names for a test, as an aid in searching

IEP (Immunoelectrophoresis)
Kappa-Free Light Chain
Lambda-Free Light Chain
Monoclonal Gammopathy of Unknown Significance (MGUS)
Multiple Myeloma
Myeloma Studies
Protein Analysis, Myeloma
Protein Electrophoresis
Special Protein Studies