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Test ID: HMDP    
Hyperimmunoglobulin M (Hyper-IgM) Defects Panel

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Test Classification Provides information regarding the medical device classification for laboratory test kits and reagents. Tests may be classified as cleared or approved by the US Food and Drug Administration (FDA) and used per manufacturer's instructions, or as products that do not undergo full FDA review and approval, and are then labeled as an Analyte Specific Reagent (ASR), Investigation Use Only (IUO) product, or a Research Use Only (RUO) product.

This test was developed using an analyte specific reagent. Its performance characteristics were determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the U.S. Food and Drug Administration.

CPT Code Information Provides guidance in determining the appropriate Current Procedural Terminology (CPT) code(s) information for each test or profile. The listed CPT codes reflect Mayo Medical Laboratories interpretation of CPT coding requirements. It is the responsibility of each laboratory to determine correct CPT codes to use for billing.

T- and B-Cell Quantitation by Flow Cytometry

86355-B cells, total count

86357-Natural killer (NK) cells, total count

86359-T cells, total count

86360-Absolute CD4/CD8 count with ratio


B-Cell Phenotyping Screen for Immunodeficiency and Immune Competence Assessment, Blood

88184-Flow cytometry, first marker

88185 x 7-Flow cytometry, each additional marker


B-Cell CD40 Expression by Flow Cytometry, Blood



X-Linked Hyper IgM Syndrome, Blood

88184-Flow cytometry, cell surface, cytoplasmic

88185 x 6-Each additional marker

LOINC® Code Information Provides guidance in determining the Logical Observation Identifiers Names and Codes (LOINC) values for the order and result codes of this test.

Test IDTest Order NameOrder LOINC Code
HMDPHyperimmunoglobulin M (Hyper-IgM) Defects PanelIn Process


Result IDTest Result NameResult LOINC Code
89009CD40 by Flow, QL, BIn Process
30296CD19+ % of total Lymphocytes8117-4
9336T-and B-Cell QN by Flow Cytometry(TBBS_)In Process
82964CD40 Ligand ExpressionIn Process
29040CD40muIg (Function)In Process
29094CD20+ % of total Lymphocytes8119-0
3321CD45 Lymph Count, Flow27071-0
3316% CD3 (T Cells)8124-0
30298CD27+ % of CD19+ B cellsIn Process
3318% CD19 (B Cells)8117-4
30300CD27+ IgM+ IgD+ % of CD19+ B cellsIn Process
30302CD27+ IgM- IgD- % of CD19+ B cellsIn Process
4054% CD16+CD56 (NK cells)18267-5
3319% CD4 (Helper Cells)8123-2
30304CD27+ IgM+ IgD- % of CD19+ B cellsIn Process
3320% CD8 (Supp'r Cells)8101-8
30306IgM+ % of CD19+ B cellsIn Process
30308CD38+ IgM- % of CD19+ B cellsIn Process
3322CD3 (T Cells)8122-4
30310CD38+ IgM+ % of CD19+ B cellsIn Process
3324CD19 (B Cells)8116-6
4055CD16+CD56 (NK cells)20402-4
30312CD21+ % of CD19+ B cellsIn Process
30314CD21- % of CD19+ B cellsIn Process
3325CD4 (Helper Cells)24467-3
3326CD8 (Supp'r Cells)14135-8
3327H/S Ratio54218-3
30299CD27+In Process
30301CD27+ IgM+ IgD+In Process
30303CD27+ IgM- IgD-In Process
30305CD27+ IgM+ IgD-In Process
30307IgM+In Process
30309CD38+ IgM-In Process
30311CD38+ IgM+In Process
30315CD21-In Process

LOINC and CPT codes are provided by the performing laboratory.