Hematology and Hematopathology

Featured Test

Acute Myeloid Leukemia (AML), FISH (Test ID: FAML)

Acute myeloid leukemia (AML) is 1 of the most common adult leukemias, with almost 10,000 new cases diagnosed per year. AML also comprises 15% of pediatric acute leukemias and accounts for the majority of infant (<1 year old) leukemias. Several subtypes of AML have been recognized (termed AML-M0, M1, M2, M3, M4, M5, M6, and M7) based on the malignant myeloid cell lineage involved. In addition to morphology, several recurrent chromosomal anomalies have been linked to specific subtypes of AML.

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Testing of Hematopoietic Neoplasms

The cytogenetics laboratory is directed by physician laboratorians who understand the clinical testing needs and complexities of appropriate test integration for all aspects of patient management, including diagnosis, prognosis, and therapy monitoring. This expertise is available to Mayo Medical Laboratories' clients through interpretive reporting and consultative services. Specialized tests required for the management of patients with hematopoietic disorders are rigorously validated and continuously monitored to ensure reliable, high-quality results. The molecular and cytogenetic laboratories work collaboratively to offer a comprehensive and practical test menu.

Optimal Test Utilization

A cellular pellet is saved in the cytogenetic laboratory for potential future testing if subsequent clinical questions arise or if other studies point to the need for further analysis with fluorescence in situ hybridization (FISH) probes. The laboratory supports ongoing development and continues to incorporate innovative platforms and testing strategies to expand the test menu as clinical needs arise.

Expert Consultants

The cytogenetic laboratory for congenital and hematologic analysis has played a leading role in establishing fluorescence in situ hybridization (FISH) as an important clinical technique. A large group of board-certified genetic counselors are also available to assist with hereditary genetic questions that may arise.

Patricia T. Greipp, DO
Co-Director

Jennelle C. Hodge, PhD
Co-Director

Nicole L. Hoppman-Chaney, PhD
Co-Director

Rhett P. Ketterling, MD
Co-Director

Robert B. Jenkins, MD, PhD
Co-Director

William R. Sukov, MD
Co-Director

Erik C. Thorland, PhD
Co-Director

Daniel L. Van Dyke, PhD
Co-Director