Alpha-2 Plasmin Inhibitor, Plasma
Method Description Describes how the test is performed and provides a method-specific reference
This assay is performed using the HemosIL Plasmin Inhibitor Kit on the Beckman Coulter ACL TOP. Patient plasma, containing alpha-2 plasmin inhibitor, is mixed with reagent containing excess plasmin. Plasmin activity in the reagent is rapidly inhibited by alpha-2 plasmin inhibitor. Residual plasmin activity is then measured using an amidolytic activity assay, in which residual plasmin lyses a synthetic chromogenic substrate and subsequently releases paranitroanline (detected at 405 nm) to a level that is inversely proportional to the amount of alpha-2 plasmin inhibitor in the sample.(Teger-Nilsson AC, Friberger P, Gyzander E: Determination of a new rapid plasmin inhibitor in human blood by means of a plasmin specific tripeptide substrate. Scand J Clin Lab Invest 1977;37:403-409)
Day(s) and Time(s) Test Performed Outlines the days and times the test is performed. This field reflects the day and time the sample must be in the testing laboratory to begin the testing process and includes any specimen preparation and processing time required before the test is performed. Some tests are listed as continuously performed, which means assays are performed several times during the day.
Monday through Friday; Varies