Antithrombin Antigen, Plasma
Method Description Describes how the test is performed and provides a method-specific reference
This assay is performed on the Beckman Coulter ACL TOP. Antithrombin antigen is determined using automated latex immunoassay (LIA) methodology. This methodology is comprised of a reagent with microlatex particles coated with specific antihuman antithrombin antibodies. Patient plasma containing antithrombin antigen is combined with the latex reagent causing the antibody-coated latex particles to agglutinate and form aggregates. The aggregates form diameters greater than the wavelength of the light (405 nm) passing through causing absorption of the light. This change in absorption is measured over time and reported as delta optical density. The increase in absorption is proportional to the concentration of antithrombin antigen present in the sample. (LaRoche P, Plassart V. Amiral J: Rapid quantitative latex immunoassays for diagnosis of thrombotic disorders. Thromb Haemost 1989;62:379)
Day(s) and Time(s) Test Performed Outlines the days and times the test is performed. This field reflects the day and time the sample must be in the testing laboratory to begin the testing process and includes any specimen preparation and processing time required before the test is performed. Some tests are listed as continuously performed, which means assays are performed several times during the day.
Monday through Friday