Plasma Cell Proliferative Disorder (PCPD), FISH
Method Description Describes how the test is performed and provides a method-specific reference
Deletions or monosomies of chromosomes 13 and 17 and copy number gains of 1q are detected using enumeration strategy probes. Centromere probes are used to detect chromosomal aneusomies for chromosomes 3, 7, 9, and 15. Translocations involving chromosome 14 (IGH) with chromosomes 4 (FGFR3), 11 (CCND1), or 16 (MAF) are detected using dual-color, dual-fusion (D-FISH) strategy probes. Rearrangement of MYC is detected using a break-apart strategy (BAP) probe. Plasma cells are identified using immunoglobulin staining techniques and antibodies (cytoplasmic immunoglobulin) for kappa and lambda. For each probe set, 50 plasma cells (if possible) are scored and the result for each probe is reported.(Unpublished Mayo method)
PDF Report Indicates whether the report includes an additional document with charts, images or other enriched information
Day(s) and Time(s) Test Performed Outlines the days and times the test is performed. This field reflects the day and time the sample must be in the testing laboratory to begin the testing process and includes any specimen preparation and processing time required before the test is performed. Some tests are listed as continuously performed, which means assays are performed several times during the day.
Samples processed Monday through Sunday. Results reported Monday through Friday, 8 a.m.-5 p.m. CST.