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Test ID: TAE    
Therapeutic Antibody by Flow Cytometry

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Method Description Describes how the test is performed and provides a method-specific reference

Flow cytometric immunophenotyping of peripheral blood, bone marrow, or tissue-derived lymphocytes is performed to assess the expression of the cell-surface antigen corresponding to the monoclonal antibody therapeutic target. The following antibody panels will be used:

-Anti-CD20 assessment: kappa/lambda/CD19/CD20

-Anti-CD25 assessment: CD25/CD19/CD3/CD45

-Anti-CD49d assessment: CD19/CD49d/CD3/CD45

-Anti-CD52 assessment: CD52/CD19/CD3/CD45

(Flow Cytometry in Clinical Diagnosis. Fourth Edition. Edited by P Keren, JP McCoy Jr, J Carey. ASCP Press, Chicago, IL, 2007)

Supplemental Report Indicates whether the report includes an additional document with charts, images or other enriched information

Yes

Day(s) and Time(s) Test Performed Outlines the days and times the test is performed. This field reflects the day and time the sample must be in the testing laboratory to begin the testing process and includes any specimen preparation and processing time required before the test is performed. Some tests are listed as continuously performed, which means assays are performed several times during the day.

Specimens are processed Monday through Saturday and reported Monday through Friday.

Analytic Time Defines the amount of time it takes the laboratory to setup and perform the test. This is defined in number of days. The shortest interval of time expressed is "same day/1 day," which means the results may be available the same day that the sample is received in the testing laboratory. One day means results are available 1 day after the sample is received in the laboratory.

1 day

Maximum Laboratory Time Defines the maximum time from specimen receipt at Mayo Medical Laboratories until the release of the test result

1 day

Specimen Retention Time Outlines the length of time after testing that a specimen is kept in the laboratory before it is discarded

Remaining specimen stored 2 weeks

Performing Laboratory Location The location of the laboratory that performs the test

Rochester