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This test is the preferred test for the confirmation of a diagnosis of porphyria cutanea tarda type II and hepatoerythropoietic porphyria
Uroporphyrinogen decarboxylase (UPGD) is deficient in cases of type II porphyria cutanea tarda (PCT). Enzyme analysis is uninformative in sporadic PCT cases.
Due to longer specimen stability, this test is the preferred test for analysis of UPGD enzyme.
The following algorithms are available in Special Instructions:
-Porphyria (Acute) Testing Algorithm
-Porphyria (Cutaneous) Testing Algorithm
High-Performance Liquid Chromatography (HPLC)/Incubation of Lysed Erythrocytes