Amyloidosis, Transthyretin-Associated Familial, Reflex, Blood
NY State Approved Indicates the status of NY State approval and if the test is orderable for NY State clients.
Diagnosis of adult individuals suspected of having transthyretin-associated familial amyloidosis
Genetics Test Information Provides information that may help with selection of the correct test or proper submission of the test request
Mass spectrometry to evaluate transthyretin (TTR) protein structure is performed first. In all cases demonstrating a structural change, the TTR gene will be further analyzed by DNA sequence analysis. If no alterations are detected, subsequent gene analysis will not be performed unless a request for AMYL / Amyloidosis, Transthyretin-Associated Familial, DNA Sequence, Blood is submitted by the ordering physician or client.
Reflex Tests Lists test(s) that may or may not be performed, at an additional charge, depending on the result and interpretation of the initial test(s)
|Test ID||Reporting Name||Available Separately||Always Performed|
|AMYL||Familial Amyloidosis, DNA Sequence||Yes||No|
Testing Algorithm Delineates situation(s) when tests are added to the initial order. This includes reflex and additional tests.
If familial amyloidosis by liquid chromatography-mass spectrometry is abnormal, DNA sequence will be performed and charged separately.
See Amyloidosis (Familial) Test Algorithm in Special Instructions.
Special Instructions and Forms Describes specimen collection and preparation information, test algorithms, and other information pertinent to test. Also includes pertinent information and consent forms to be used when requesting a particular test
Liquid Chromatography-Mass Spectrometry (LC-MS)