Porphyrins Evaluation, Washed Erythrocytes
NY State Approved Indicates the status of NY State approval and if the test is orderable for NY State clients.
Diagnosis of erythropoietic protoporphyria and congenital erythropoietic porphyria
Evaluation of chronic intoxication from exposure to a variety of agents including heavy metals and chemicals
Differentiating iron-deficiency anemia from other causes of elevated porphyrin levels
Reflex Tests Lists test(s) that may or may not be performed, at an additional charge, depending on the result and interpretation of the initial test(s)
|Test ID||Reporting Name||Available Separately||Always Performed|
|PPFR||Protoporphyrins, Fractionation||Yes, (order PPFE)||No|
Testing Algorithm Delineates situation(s) when tests are added to the initial order. This includes reflex and additional tests.
Testing begins with total RBC porphyrins. If the result is <80 mcg/dL, it is normal and testing is complete. If the total RBC porphyrin value is >80 mcg/dL, fractionation assays will be performed at an additional charge to identify the porphyrin involved. The protoporphyrin fractionation yields free protoporphyrin and zinc-complexed protoporphyrin. Depending on this result, porphyrins fractionation may be added, which fractionates and individually quantitates RBC porphyrins (uroporphyrin, coproporphyrin, and protoporphyrin).
The following algorithms are available in Special Instructions:
-Porphyria (Acute) Testing Algorithm
-Porphyria (Cutaneous) Testing Algorithm
Special Instructions and Forms Describes specimen collection and preparation information, test algorithms, and other information pertinent to test. Also includes pertinent information and consent forms to be used when requesting a particular test
PFR: High-Performance Liquid Chromatography (HPLC)
Reporting Name A shorter/abbreviated version of the Published Name for a test; an abbreviated test name
Erythropoietic Protoporphyria (EPP)
Free Erythrocyte Porphyrin (FEP)
Protoporphyrins, Total, Erythrocytes
Red Blood Cell (RBC) Porphyrins