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Test ID: PLHBB    
Plasma Hemoglobin, Plasma

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Useful For Suggests clinical disorders or settings where the test may be helpful

Determining whether hemolysis is occurring such as from:

-Transfusion reaction

-Mechanical fragmentation of red blood cells

Clinical Information Discusses physiology, pathophysiology, and general clinical aspects, as they relate to a laboratory test

Plasma normally contains no free hemoglobin ie, no hemoglobin that is not contained in erythrocytes.

 

Significant amounts of hemoglobin occur in plasma following hemolysis such as might result from a transfusion reaction or mechanical fragmentation of red blood cells during cardiac surgery.

Reference Values Describes reference intervals and additional information for interpretation of test results. May include intervals based on age and sex when appropriate. Intervals are Mayo-derived, unless otherwise designated. If an interpretive report is provided, the reference value field will state this.

TOTAL HEMOGLOBIN

> or =12 months: 0.0-15.2 mg/dL

Reference values have not been established for patients who are less than 12 months of age.

 

OXYHEMOGLOBIN

> or =12 months: 0.0-12.4 mg/dL

Reference values have not been established for patients who are less than 12 months of age.

Interpretation Provides information to assist in interpretation of the test results

Total hemoglobin:

> or =12 months: 0.0-15.2 mg/dL

Reference values have not been established for patients who are less than 12 months of age.

 

Oxyhemoglobin:

> or =12 months: 0.0-12.4 mg/dL

Reference values have not been established for patients who are less than 12 months of age.

Cautions Discusses conditions that may cause diagnostic confusion, including improper specimen collection and handling, inappropriate test selection, and interfering substances

Test should not be performed on serum; hemoglobin is liberated from red blood cells during clotting.

 

Drawing blood specimens for plasma hemoglobin measurement should be done with considerable care to avoid causing hemolysis.

 

Bilirubin is a known interference with this assay. Elevated bilirubin levels interfere with the quantitation of the total plasma hemoglobin.

Clinical Reference Provides recommendations for further in-depth reading of a clinical nature

Fairbanks VF, Ziesmer SC, O'Brien PC: Methods for measuring plasma hemoglobin in micromolar concentration compared. Clin Chem 1992;38:132-140