Mitochondrial Respiratory Chain Enzyme Analysis - Skin
NY State Approved Indicates the status of NY State approval and if the test is orderable for NY State clients.
Reporting Name A shorter/abbreviated version of the Published Name for a test; an abbreviated test name
Electron Transport Chain Enzymes
Electron Transport Chain FORWARD
Respiratory Chain Complexes FORWARD
Respiratory Chain Complexes FORWARD
Specimen Type Describes the specimen type needed for testing
Specimen Required Defines the optimal specimen. This field describes the type of specimen required to perform the test and the preferred volume to complete testing. The volume allows automated processing, fastest throughput and, when indicated, repeat or reflex testing.
2 T-25 flasks(s) filled to neck with culture media. Maintain sterility
and forward promptly at ambient temperature.
Specimens other than
Fibroblasts, skin biopsy
Anticoagulants other than
Specimen Stability Information Provides a description of the temperatures required to transport a specimen to the laboratory. Alternate acceptable temperature(s) are also included.
Reference Values Describes reference intervals and additional information for interpretation of test results. May include intervals based on age and sex when appropriate. Intervals are Mayo-derived, unless otherwise designated. If an interpretive report is provided, the reference value field will state this.
A final report will be faxed under separate cover.
Test Performed by: Baylor Medical Genetics Laboratories
2450 Holcombe Blvd.
Houston, TX 77021
Method Description Describes how the test is performed and provides a method-specific reference
The respiratory chain enzyme activities are measured at 30 C using a
temperature-controlled spectrophotometer. The activities of complex I
(Ferricyanide:NADH dehydrogenase), complex II (succinate
dehydrogenase), complex I+III (NADH:cytochrome c oxidoreductase),
complex II+III (succinate:cytochrome c reductase) and complex IV
(cytochrome c oxidase) are assayed using different electron acceptors/
donors. The activities of complex I+III and II+III were measured by
following the reduction of cytochrome c at 550 nm, of complex I by
following the oxidation of NADH at 340 nm, of complex II by following
the reduction of 2,6-dichloroindophenol (DCIP) at 600 nm and of complex
IV by following the oxidation of reduced cytochrome c at 550 nm. Values
are normalized to citrate synthase when it exceeds 1 SD from the mean.
Day(s) and Time(s) Test Performed Outlines the days and times the test is performed. This field reflects the day and time the sample must be in the testing laboratory to begin the testing process and includes any specimen preparation and processing time required before the test is performed. Some tests are listed as continuously performed, which means assays are performed several times during the day.
Analytic Time Defines the amount of time it takes the laboratory to setup and perform the test. This is defined in number of days. The shortest interval of time expressed is "same day/1 day," which means the results may be available the same day that the sample is received in the testing laboratory. One day means results are available 1 day after the sample is received in the laboratory.
Maximum Laboratory Time Defines the maximum time from specimen receipt at Mayo Medical Laboratories until the release of the test result
Performing Laboratory Location The location of the laboratory that performs the test
Baylor Medical Genetics Laboratories
CPT Code Information Provides guidance in determining the appropriate Current Procedural Terminology (CPT) code(s) information for each test or profile. The listed CPT codes reflect Mayo Medical Laboratories interpretation of CPT coding requirements. It is the responsibility of each laboratory to determine correct CPT codes to use for billing.
LOINC® Code Information Provides guidance in determining the Logical Observation Identifiers Names and Codes (LOINC) values for the result codes returned for this test or profile.
|Result ID||Reporting Name||LOINC Code|
|Z1751||Electron Transport Chain Enzymes||In Process|