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Test ID: FMNM
Monoamine Neurotransmitter Metabolites/Amines

Secondary ID A test code used for billing and in test definitions created prior to November 2011

91829

NY State Approved Indicates the status of NY State approval and if the test is orderable for NY State clients.

Yes

Method Name A short description of the method used to perform the test

HPLC and electrochemical detection

Reporting Name A shorter/abbreviated version of the Published Name for a test; an abbreviated test name

Monoamine Neurotransmitter

Specimen Type Describes the specimen type needed for testing

CSF

Specimen Required Defines the optimal specimen. This field describes the type of specimen required to perform the test and the preferred volume to complete testing. The volume allows automated processing, fastest throughput and, when indicated, repeat or reflex testing.

REQUIRED:

       1.      Baylor collection kit (MML Supply T612) required.

Each collection kit contains 5 microcentrifuge tubes

in a cardboard holder. Tube #3 contains antioxidants

necessary to protect the same integrity. One set of tubes

is required per patient.

  1. Baylor request form and collection protocol.
  2. Collection date
  3. Date of birth
  4. Current medications and relevant history

 

COLLECTION PROTOCOL

1)      CSF should be collected from the first drop into the tubes in

the numbered order. Fill each tube to the marked line with

the required volumes.

Tube 1:  0.5 mL

Tube 2:  0.5 mL

Tube 3:  1.0 mL (contains antioxidants necessary to protect

                                 the sample integrity)

Tube 4:  1.0 mL

Tube 5:  0.5 mL

- If samples not blood contaminated should be placed on dry

  ice at bedside

- If samples are blood contaminated, the tubes should immediately

  be centrifuged (prior to freezing) and the clear CSF transferred to

  new similarly labeled tubes, then frozen.

-Store samples at -80 until they can be shipped. 

2)       Complete Baylor Neuropharmacology request form. Include

test required, sample date, date of birth, current medications

and relevant history.

3)       Label tubes with patient name and ID number, leaving the tube

number viewable.

4)       Place samples inside a specimen transport bag and the Baylor

request forms inside the pouch of the transport bag.

        5)    Ship samples frozen on dry ice.

Reject Due To Identifies specimen types and conditions that may cause the specimen to be rejected

Specimens other than

CSF

Anticoagulants other than

Use Baylor collection kit (MML Supply T612)

Hemolysis

NA

Thawing

Warm reject; Cold reject

Lipemia

NA

Icteric

NA

Specimen Stability Information Provides a description of the temperatures required to transport a specimen to the laboratory. Alternate acceptable temperature(s) are also included.

Specimen TypeTemperatureTime
CSFFrozen

Reference Values Describes reference intervals and additional information for interpretation of test results. May include intervals based on age and sex when appropriate. Intervals are Mayo-derived, unless otherwise designated. If an interpretive report is provided, the reference value field will state this.

CSF Metabolite Age related reference ranges (values

expressed in nmol/L)

 

5-Hydroxyindoleacetic acid (5HIAA)  

Newborn 0-73 days                      208-1159     

Infant 73 days-6 months               179-711

Toddler 6 months-2 years              129-520

Child 2-5 years                            74-345

Older Child 5-10 years                   66-338

Adolescent 10-15 years                67-189

Adult > 15 years                          67-140

 

Homovanillic acid (HVA)  

Newborn 0-73 days                      337-1299     

Infant 73 days-6 months               450-1132

Toddler 6 months-2 years              294-1115

Child 2-5 years                            233-918

Older Child 5-10 years                   218-852

Adolescent 10-15 years                167-852

Adult > 15 years                          145-852

 

3-O-methyldopa (3-OMD)

Newborn 0-73 days                      0-300     

Infant 73 days-6 months               0-300

Toddler 6 months-2 years              0-300

Child 2-5 years                            0-150

Older Child 5-10 years                   0-100

Adolescent 10-15 years                0-100

Adult > 15 years                          0-100

 

Test Performed By: Baylor Institute of Metabolic Disease

                          Baylor Research Institute

                          3812 Elm Street

                          Dallas, TX 75226

Day(s) and Time(s) Test Performed Outlines the days and times the test is performed. This field reflects the day and time the sample must be in the testing laboratory to begin the testing process and includes any specimen preparation and processing time required before the test is performed. Some tests are listed as continuously performed, which means assays are performed several times during the day.

Varies

Analytic Time Defines the amount of time it takes the laboratory to setup and perform the test. This is defined in number of days. The shortest interval of time expressed is "same day/1 day," which means the results may be available the same day that the sample is received in the testing laboratory. One day means results are available 1 day after the sample is received in the laboratory.

7 days

Maximum Laboratory Time Defines the maximum time from specimen receipt at Mayo Medical Laboratories until the release of the test result

9 - 11 days

Performing Laboratory Location The location of the laboratory that performs the test

Baylor University M

CPT Code Information Provides guidance in determining the appropriate Current Procedural Terminology (CPT) code(s) information for each test or profile. The listed CPT codes reflect Mayo Medical Laboratories interpretation of CPT coding requirements. It is the responsibility of each laboratory to determine correct CPT codes to use for billing.

82492

LOINC® Code Information Provides guidance in determining the Logical Observation Identifiers Names and Codes (LOINC) values for the result codes returned for this test or profile.

Result IDReporting NameLOINC Code
Z01065-Hydroxyindoleacetic acid (5HIAA)In Process
Z0107Homovanillic acid (HVA)In Process
Z01083-O-methyldopa (3-OMD)In Process
Z0109InterpretationIn Process