Test ID: 9172
Bone Marrow Biopsy
Secondary ID 
A test code used for billing and in test definitions created prior to November 2011
NY State Approved Indicates the status of NY State approval and if the test is orderable for NY State clients.
Useful For Suggests clinical disorders or settings where the test may be helpful
The evaluation of the bone marrow biopsy for diagnosis of hematologic and/or non hematologic diseases
Special Instructions and Forms Describes specimen collection and preparation information, test algorithms, and other information pertinent to test. Also includes pertinent information and consent forms to be used when requesting a particular test
Method Name A short description of the method used to perform the test
Includes tissue processing, hematoxylin-and-eosin stain, iron stain, and additional stains if necessary for interpretation.
A pathology consultation is also included and is charged separately.
Reporting Name A shorter/abbreviated version of the Published Name for a test; an abbreviated test name
Aliases Lists additional common names for a test, as an aid in searching
Marrow, Bone
Tissue Processing (Bone Marrow Biopsy)
Specimen Type Describes the specimen type needed for testing
Specimen Required Defines the optimal specimen. This field describes the type of specimen required to perform the test and the preferred volume to complete testing. The volume allows automated processing, fastest throughput and, when indicated, repeat or reflex testing.
Specimen Type: Bone marrow, fixed marrow core
Container/Tube: Bone marrow container with saline
Specimen Volume: Entire specimen
Collection Instructions: Fix specimen in formalin for 1 to 2 hours.
Additional Information:
1. A pathology/diagnostic report and a brief history are required.
2. When ordering this test, 5434 Hematopathology Consultation must be ordered on the same order.
3. See Laboratory Screening Tests for Suspected Multiple Myeloma in Special Instructions.
Specimen Minimum Volume Defines the amount of specimen required to perform an assay once, including instrument and container dead space. Submitting the minimum specimen volume makes it impossible to repeat the test or perform confirmatory or perform reflex testing. In some situations, a minimum specimen volume may result in a QNS (quantity not sufficient) result, requiring a second specimen to be collected.
Reject Due To Identifies specimen types and conditions that may cause the specimen to be rejected
| Hemolysis | NA |
| Lipemia | NA |
| Icterus | NA |
| Other | Bone marrow core |
Specimen Stability Information Provides a description of the temperatures required to transport a specimen to the laboratory. Alternate acceptable temperature(s) are also included.
| Specimen Type | Temperature | Time |
|---|---|---|
| Bone Marrow | Ambient | |
Clinical Information Discusses physiology, pathophysiology, and general clinical aspects, as they relate to a laboratory test
Blood cells are normally produced from bone marrow. Various diseases may affect the blood cell production in the bone marrow, especially the hematologic diseases and the non-hematologic diseases involving the bone marrow.
See Laboratory Screening Tests for Suspected Multiple Myeloma in Special Instructions. Also see Diagnosis and Monitoring of Multiple Myeloma in Publications.
Reference Values Describes reference intervals and additional information for interpretation of test results. May include intervals based on age and sex when appropriate. Intervals are Mayo-derived, unless otherwise designated. If an interpretive report is provided, the reference value field will state this.
An interpretive report will be provided.
Interpretation Provides information to assist in interpretation of the test results
The laboratory will provide an interpretive report of hematoxylin and eosin stained slides, iron stain, and additional stains if necessary.
Cautions Discusses conditions that may cause diagnostic confusion, including improper specimen collection and handling, inappropriate test selection, and interfering substances
Specimens must be fixed in formalin for 1 to 2 hours; then the fixed marrow core should be sent to the laboratory in buffered saline.
Clinical Reference Provides recommendations for further in-depth reading of a clinical nature
Kass L: Procedures for performing aspiration and biopsy of bone marrow. In Bone Marrow Interpretation. 2nd edition. Philadelphia, JB Lippincott, 1979
Method Description Describes how the test is performed and provides a method-specific reference
Paraffin section with hematoxylin and iron stains. (Hanson CA: unpublished Mayo information)
Day(s) and Time(s) Test Performed Outlines the days and times the test is performed. This field reflects the day and time the sample must be in the testing laboratory to begin the testing process and includes any specimen preparation and processing time required before the test is performed. Some tests are listed as continuously performed, which means assays are performed several times during the day.
Monday through Friday; Varies
Analytic Time Defines the amount of time it takes the laboratory to setup and perform the test. This is defined in number of days. The shortest interval of time expressed is "same day/1 day," which means the results may be available the same day that the sample is received in the testing laboratory. One day means results are available 1 day after the sample is received in the laboratory.
Maximum Laboratory Time Defines the maximum time from specimen receipt at Mayo Medical Laboratories until the release of the test result
Specimen Retention Time Outlines the length of time after testing that a specimen is kept in the laboratory before it is discarded
Performing Laboratory Location The location of the laboratory that performs the test
CPT Code Information Provides guidance in determining the appropriate Current Procedural Terminology (CPT) code(s) information for each test or profile. The listed CPT codes reflect Mayo Medical Laboratories interpretation of CPT coding requirements. It is the responsibility of each laboratory to determine correct CPT codes to use for billing.
88305-Surgical pathology, gross and microscopic
88311-Decalcification
LOINC® Code Information Provides guidance in determining the Logical Observation Identifiers Names and Codes (LOINC) values for the result codes returned for this test or profile.
| Result ID | Reporting Name | LOINC Code |
|---|---|---|
| 9172 | Bone Marrow fix sect | In Process |
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