Test ID: FPTHC
PTH Accuratio Comprehensive Profile
Secondary ID 
A test code used for billing and in test definitions created prior to November 2011
NY State Approved Indicates the status of NY State approval and if the test is orderable for NY State clients.
Method Name A short description of the method used to perform the test
Immunoradiometric assay (IRMA)
Reporting Name A shorter/abbreviated version of the Published Name for a test; an abbreviated test name
Aliases Lists additional common names for a test, as an aid in searching
Specimen Type Describes the specimen type needed for testing
Specimen Required Defines the optimal specimen. This field describes the type of specimen required to perform the test and the preferred volume to complete testing. The volume allows automated processing, fastest throughput and, when indicated, repeat or reflex testing.
Draw blood in a lavender-top (EDTA) tube(s). Spin down and
send 2 mL EDTA plasma frozen in a plastic vial.
Note: Processing of samples should be completed within one hour
of blood collection
Reject Due To Identifies specimen types and conditions that may cause the specimen to be rejected
| Specimens other than | Plasma |
| Anticoagulants other than | EDTA |
| Hemolysis | NA |
| Thawing | Warm reject; Cold reject |
| Lipemia | NA |
| Icteric | NA |
Specimen Stability Information Provides a description of the temperatures required to transport a specimen to the laboratory. Alternate acceptable temperature(s) are also included.
| Specimen Type | Temperature | Time |
|---|---|---|
| Plasma EDTA | Frozen | |
Reference Values Describes reference intervals and additional information for interpretation of test results. May include intervals based on age and sex when appropriate. Intervals are Mayo-derived, unless otherwise designated. If an interpretive report is provided, the reference value field will state this.
COMPREHENSIVE PROFILE
TOTAL PTH Reference Range: 14.0-66.0 pg/mL
CAP PTH Reference Range: 5.0-39.0 pg/mL
CIP VALUE Reference Range: 2.5-29.0 pg/mL
CAP/CIP Reference Range: 1.1-6.9 ratio
Low ratio or PTH values are associated with Adynamic bone turnover
status for an ESRD patient.
Total PTH:
Total Intact PTH is the sum of CAP PTH and N-truncated PTH
fragment (likely 7-84) Total PTH = Intact PTH = CAP + CIP.
FDA approved.
CAP PTH:
CAP stands for Cyclase Activating PTH and is the same as
Whole PTH which is 1-84 PTH and which raises bone turnover.
FDA approved.
CIP VALUE:
CIP stands for Cyclase Inactive PTH and the N-truncated PTH
fragment, likely 7-84 PTH. CIP = Total PTH – CAP.
CAP/CIP:
CAP/CIP ratio is a calculated value and has been shown to be
93% predictive of bone turnover for the ESRD patient, however,
bone biopsy is 100% predictive, therefore, clinical correlation
is recommended.
Reference ranges were established using a 95% reference
interval on a normal population with normal functioning kidneys.
These reference ranges should not be applied to ESRD
patients with impaired or non-functioning renal function.
TEST PERFORMED BY:
SCANTIBODIES CLINICAL LABORATORY, INC.
9236 ABRAHAM WAY
SANTEE, CA 92701
Clinical Reference Provides recommendations for further in-depth reading of a clinical nature
REFERENCES:
CAP reference range 90-170 pgm/mL & Ratio <1.4 = Adynamic
Bone Disease
Tokumoto, A J Amer Soc Nephrol 2003 (Nov); 14:702
Tokumoto, A J Amer Soc Nephrol 2003 (Nov); 14:700
CAP/CIP Ratio 93% predictive:
Faugere M-C, Geng Z, Mawad H, Friedler RM, Gao P,
Cantor T, Malluche H. Kidney Int 2001; 60: 1460-1468.
Total PTH>1000 pg/mL & RATIO <or=1.4=High Bone Turnover
American Journal of Kidney Diseases, Vol 26, No4 (Oct),
1995: pp622-31
TEST PERFORMED BY:
SCANTIBODIES CLINICAL LABORATORY, INC.
9236 ABRAHAM WAY
SANTEE, CA 92701
Day(s) and Time(s) Test Performed Outlines the days and times the test is performed. This field reflects the day and time the sample must be in the testing laboratory to begin the testing process and includes any specimen preparation and processing time required before the test is performed. Some tests are listed as continuously performed, which means assays are performed several times during the day.
Varies
Analytic Time Defines the amount of time it takes the laboratory to setup and perform the test. This is defined in number of days. The shortest interval of time expressed is "same day/1 day," which means the results may be available the same day that the sample is received in the testing laboratory. One day means results are available 1 day after the sample is received in the laboratory.
Maximum Laboratory Time Defines the maximum time from specimen receipt at Mayo Medical Laboratories until the release of the test result
Performing Laboratory Location The location of the laboratory that performs the test
CPT Code Information Provides guidance in determining the appropriate Current Procedural Terminology (CPT) code(s) information for each test or profile. The listed CPT codes reflect Mayo Medical Laboratories interpretation of CPT coding requirements. It is the responsibility of each laboratory to determine correct CPT codes to use for billing.
83970\x2
LOINC® Code Information Provides guidance in determining the Logical Observation Identifiers Names and Codes (LOINC) values for the result codes returned for this test or profile.
| Result ID | Reporting Name | LOINC Code |
|---|---|---|
| Z1597 | Total PTH | In Process |
| Z1594 | CAP PTH | In Process |
| Z1595 | CIP Value | In Process |
| Z1596 | CAP/CIP | In Process |
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