Test ID: FBBAB
Lyme Disease Antibody Index for CNS Infection
NY State Approved 
Indicates the status of NY State approval and if the test is orderable for NY State clients.
Profile Information A profile is a group of laboratory tests that are ordered and performed together under a single Mayo Test ID. Profile information lists the test performed, inclusive of the test fee, when a profile is ordered and includes reporting names and individual availability.
| Test ID | Reporting Name | Available Separately | Always Performed |
|---|---|---|---|
| FZ003 | Lyme Disease Ab Index | No | Yes |
| FZ004 | Albumin Ratio | No | Yes |
Method Name A short description of the method used to perform the test
Enzyme Linked Immunosorbent Assay (ELISA) and Nephelometry (NEPH)
Reporting Name A shorter/abbreviated version of the Published Name for a test; an abbreviated test name
Aliases Lists additional common names for a test, as an aid in searching
Lyme Index FORWARD
Specimen Type Describes the specimen type needed for testing
Serum
Specimen Required Defines the optimal specimen. This field describes the type of specimen required to perform the test and the preferred volume to complete testing. The volume allows automated processing, fastest throughput and, when indicated, repeat or reflex testing.
Requires Serum AND CSF
Draw blood in a red-top tube(s) (Serum gel tube is acceptable.)
Spin down and submit 2 mL refrigerate serum.
Collect 2 mL CSF in a sterile plastic vial and submit refrigerate.
Note: Serum and CSF must be drawn within 24 hours of each
other.
Specimen Minimum Volume Defines the amount of specimen required to perform an assay once, including instrument and container dead space. Submitting the minimum specimen volume makes it impossible to repeat the test or perform confirmatory or perform reflex testing. In some situations, a minimum specimen volume may result in a QNS (quantity not sufficient) result, requiring a second specimen to be collected.
Reject Due To Identifies specimen types and conditions that may cause the specimen to be rejected
| Specimens other than | Serum and CSF |
| Anticoagulants other than | NA |
| Hemolysis | NA |
| Thawing | NA |
| Lipemia | NA |
| Icteric | NA |
Specimen Stability Information Provides a description of the temperatures required to transport a specimen to the laboratory. Alternate acceptable temperature(s) are also included.
| Specimen Type | Temperature | Time |
|---|---|---|
| CSF | Refrigerated (preferred) | 14 days |
| Frozen | 30 days | |
| Ambient | 5 days | |
| Serum | Refrigerated (preferred) | 14 days |
| Frozen | 30 days | |
| Ambient | 5 days |
Reference Values Describes reference intervals and additional information for interpretation of test results. May include intervals based on age and sex when appropriate. Intervals are Mayo-derived, unless otherwise designated. If an interpretive report is provided, the reference value field will state this.
Lyme Disease Antibody Index:
< or = 1.0 Negative
1.1 - 1.2 Equivocal
> or = 1.3 Positive
Control Antibody Index: < or = 1.0
Albumin Ratio: <0.0078
The Lyme Disease Antibody Index is used as an aid for the diagnosis of neuroborreliosis. An increased Lyme Disease Antibody Index (>1.2), accompanied by a Control Antibody Index of less than 1.0 and an Albumin Ratio of less than 0.0078, is strong evidence for intrathecal synthesis of organism-specific antibody, and thus CNS B. burgdorferi infection. Elevation of either the control antibody index, the Albumin Ratio, or both may indicate leakage of antibody across the blood-brain barrier which may falsely elevate the Lyme Disease Antibody Index.
Test Performed by: Focus Diagnostics, Inc.
5785 Corporate Avenue
Cypress, CA 90630-4750
Day(s) and Time(s) Test Performed Outlines the days and times the test is performed. This field reflects the day and time the sample must be in the testing laboratory to begin the testing process and includes any specimen preparation and processing time required before the test is performed. Some tests are listed as continuously performed, which means assays are performed several times during the day.
Tuesday and Friday
Analytic Time Defines the amount of time it takes the laboratory to setup and perform the test. This is defined in number of days. The shortest interval of time expressed is "same day/1 day," which means the results may be available the same day that the sample is received in the testing laboratory. One day means results are available 1 day after the sample is received in the laboratory.
Maximum Laboratory Time Defines the maximum time from specimen receipt at Mayo Medical Laboratories until the release of the test result
Specimen Retention Time Outlines the length of time after testing that a specimen is kept in the laboratory before it is discarded
Performing Laboratory Location The location of the laboratory that performs the test
CPT Code Information Provides guidance in determining the appropriate Current Procedural Terminology (CPT) code(s) information for each test or profile. The listed CPT codes reflect Mayo Medical Laboratories interpretation of CPT coding requirements. It is the responsibility of each laboratory to determine correct CPT codes to use for billing.
82040
82042
82784/x2
86618/x4
LOINC® Code Information Provides guidance in determining the Logical Observation Identifiers Names and Codes (LOINC) values for the result codes returned for this test or profile.
| Result ID | Reporting Name | LOINC Code |
|---|---|---|
| Z0677 | Lyme Disease Ab Index | In Process |
| Z0359 | Albumin Ratio | In Process |
| Z0360 | Interpretation | In Process |
| Z0358 | Control Ab Index | In Process |
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