Test ID: FPAP2
Premature Adrenarche Profile II (Androstenedione, DHEA, 17-OH-
Pregnenolone, 17-Alpha-Hydroxyprogesterone, Testosterone)
Secondary ID 
A test code used for billing and in test definitions created prior to November 2011
NY State Approved Indicates the status of NY State approval and if the test is orderable for NY State clients.
Method Name A short description of the method used to perform the test
Radioimmunoassay (RIA)
High Performance Liquid Chromatography/Tandem Mass Spectro-
metry (LC-MS/MS)
Reporting Name A shorter/abbreviated version of the Published Name for a test; an abbreviated test name
Aliases Lists additional common names for a test, as an aid in searching
PAP II FORWARD
Premature Adrenarche Prf II FORWARD
Premature Adrenarche Profile II FORWARD
Premature Andrenarche Profile 2 FORWARD
Specimen Type Describes the specimen type needed for testing
Specimen Required Defines the optimal specimen. This field describes the type of specimen required to perform the test and the preferred volume to complete testing. The volume allows automated processing, fastest throughput and, when indicated, repeat or reflex testing.
Draw blood in a plain, red-top tube(s) or serum gel tube(s). Separate
within one hour and send 2.0 mL of serum frozen in plastic vial.
Specimens drawn in serum gel tube(s) must be poured off into a
plastic screw cap vial before freezing.
Specimen Minimum Volume Defines the amount of specimen required to perform an assay once, including instrument and container dead space. Submitting the minimum specimen volume makes it impossible to repeat the test or perform confirmatory or perform reflex testing. In some situations, a minimum specimen volume may result in a QNS (quantity not sufficient) result, requiring a second specimen to be collected.
Reject Due To Identifies specimen types and conditions that may cause the specimen to be rejected
| Specimens other than | Serum |
| Anticoagulants other than | NA |
| Hemolysis | NA |
| Thawing | Warm reject; Cold reject |
| Lipemia | NA |
| Icteric | NA |
Specimen Stability Information Provides a description of the temperatures required to transport a specimen to the laboratory. Alternate acceptable temperature(s) are also included.
| Specimen Type | Temperature | Time |
|---|---|---|
| Serum | Frozen | |
Reference Values Describes reference intervals and additional information for interpretation of test results. May include intervals based on age and sex when appropriate. Intervals are Mayo-derived, unless otherwise designated. If an interpretive report is provided, the reference value field will state this.
Androstenedione, Mass Spec
Units: ng/dL
Age Range
Premature (26-28w) Day 4 63-935
Premature (31-35w) Day 4 50-449
Full Term (1-7 days) <10-279
Levels decrease rapidly to <52 ng/dL after one week.
1-11m <10-37
Androstenedione gradually decreases during the first
six months to prepubertal levels.
Prepubertal Children: <10-17
Adult Males 44-186
Adult Females 28-230
Females Postmenopasual <10-93
Females
Tanner Stages Age (years) Range
1 <9.2 <10-17
2 9.2-13.7 <10-72
3 10.0-14.4 50-170
4 10.7-15.6 47-208
5 11.8-18.6 50-224
Males
Tanner Stages Age (years) Range
1 <9.8 <10-17
2 9.8-14.5 <10-33
3 10.7-15.4 17-72
4 11.8-16.2 15-115
5 12.8-17.3 33-192
Dehydroepiandrosterone (DHEA)
Units: ng/dL
Age Range
1-5 yrs <68
6-7 yrs <111
8-10 yrs <186
11-12 yrs <202
13-14 yrs <319
15-16 yrs 39 - 481
17-19 yrs 40 - 491
20-49 yrs 31 - 701
> or = 50 yrs 21 - 402
17-OH Pregnenolone, Mass Spec
Units: ng/dL
Age Range
Premature (26-28w) Day 4 375 - 3559
Premature (31-35w) Day 4 64 - 2380
3 Days 10 - 829
1 - 5m 36 - 763
6 - 11m 42 - 540
12 - 23m 14 - 207
24m-5y 10 - 103
6 - 9y 10 - 186
Pubertal 44 - 235
Adults 53 - 357
17-Alpha-Hydroxyprogesterone
Units: ng/dL
Age Range
Premature (26-28w) Day 4 124 - 841
Premature (31-35w) Day 4 26 - 568
Full-Term Day 3 <78
Males
Levels increase after the first week to peak values ranging from
40-200 ng/dL between 30 and 60 days. Values then decline to a
prepubertal value of <91 before one year.
Prepubertal <91
Adult Males 27 - 199
Females
(1 - 11 Months) 13 - 106
Prepubertal <91
Adult Females
Follicular 15 - 70
Luteal 35 - 290
Females
Tanner Stages Age (years) Range
1 <9.2 <83
2 9.2-13.7 11-98
3 10.0-14.4 11-155
4 10.7-15.6 18-230
5 11.8-18.6 20-265
Males
Tanner Stages Age (years) Range
1 <9.8 <91
2 9.8-14.5 <116
3 10.7-15.4 10-138
4 11.8-16.2 29-180
5 12.8-17.3 24-175
Testosterone, Serum (Total)
Units:ng/dL
Age Range
Males
Premature (26-28w) Day 4 59 -125
Premature (31-35w) Day 4 37 -198
Newborns 75 - 400
1 - 7m: Levels decrease rapidly the first week to 20-50, then
increase to 60-400 between 20-60 days. Levels then decline to
prepubertal range levels of <2.5 - 10 by seven months.
Females
Premature (26 - 28w) Day 4 5 - 16
Premature (31 - 35w) Day 4 5 - 22
Newborns 20 - 64
1 - 7m: Levels decrease during the first month to less than 10
and remain there until puberty.
Prepubertal Males and Females <2.5 - 10 ng/dL
Adult Males >18 years 348 - 1197
Adult Females
Premenopausal: 10 - 55
Postmenopausal: 7 - 40
Males
Tanner Stage Age (years) Male
1 <9.8 <2.5 - 10
2 9.8 - 14.5 18 - 150
3 10.7 - 15.4 100 - 320
4 11.8 - 16.2 200 - 620
5 12.8 - 17.3 350 - 970
Females
Tanner Stage Age (years) Female
1 <9.2 <2.5 - 10
2 9.2 - 13.7 7 - 28
3 10.0 - 14.4 15 - 35
4 10.7 - 15.6 13 - 32
5 11.8 - 18.6 20 - 38
Test Performed By: Esoterix Endocrinology
4301 Lost Hills Road
Calabasas Hills, CA 91301
Day(s) and Time(s) Test Performed Outlines the days and times the test is performed. This field reflects the day and time the sample must be in the testing laboratory to begin the testing process and includes any specimen preparation and processing time required before the test is performed. Some tests are listed as continuously performed, which means assays are performed several times during the day.
Monday, Tuesday, Thursday
Analytic Time Defines the amount of time it takes the laboratory to setup and perform the test. This is defined in number of days. The shortest interval of time expressed is "same day/1 day," which means the results may be available the same day that the sample is received in the testing laboratory. One day means results are available 1 day after the sample is received in the laboratory.
Maximum Laboratory Time Defines the maximum time from specimen receipt at Mayo Medical Laboratories until the release of the test result
Performing Laboratory Location The location of the laboratory that performs the test
CPT Code Information Provides guidance in determining the appropriate Current Procedural Terminology (CPT) code(s) information for each test or profile. The listed CPT codes reflect Mayo Medical Laboratories interpretation of CPT coding requirements. It is the responsibility of each laboratory to determine correct CPT codes to use for billing.
82157/Androstenedione
82626/DHEA
84143/17-OH-Pregnenolone
83498/17-OH-Progesterone
84403/Testosterone
LOINC® Code Information Provides guidance in determining the Logical Observation Identifiers Names and Codes (LOINC) values for the result codes returned for this test or profile.
| Result ID | Reporting Name | LOINC Code |
|---|---|---|
| Z1890 | Dehydroepiandrosterone (DHEA) | In Process |
| Z1892 | 17-OH Pregnenolone | In Process |
| Z1898 | 17-Alpha-Hydroxyprogesterone | In Process |
| Z1899 | Androstenedione | In Process |
| Z1905 | Testosterone, Serum (Total) | In Process |
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