Test ID: FCAH6
CAH Pediatric Profile 6, Comprehensive Screen (Androstenedione,
Specific S, Cortisol, DHEA, DOC, 17-OH-Prenenolone, Progesterone,
17-OH-Progesterone, Testosterone)
Secondary ID 
A test code used for billing and in test definitions created prior to November 2011
NY State Approved Indicates the status of NY State approval and if the test is orderable for NY State clients.
Method Name A short description of the method used to perform the test
Radioimmunoassay (RIA)
High Performance Liquid Chromatography/Tandem Mass
Spectrometry (LC-MS/MS)
Reporting Name A shorter/abbreviated version of the Published Name for a test; an abbreviated test name
Aliases Lists additional common names for a test, as an aid in searching
CAH Profile 6-Comprehensive FORWARD
Congenital Adrenal Hyperplasia, Comprehensive Screen FORWARD
Specimen Type Describes the specimen type needed for testing
Specimen Required Defines the optimal specimen. This field describes the type of specimen required to perform the test and the preferred volume to complete testing. The volume allows automated processing, fastest throughput and, when indicated, repeat or reflex testing.
Draw blood in a plain, red-top tube(s). Spin down and separate
within 1 hour of collection and send 3.5 mL of serum frozen in
plastic vial. Specimens drawn in serum gel tube(s) must be
poured off into a plastic screw cap vial before freezing.
Specimen Minimum Volume Defines the amount of specimen required to perform an assay once, including instrument and container dead space. Submitting the minimum specimen volume makes it impossible to repeat the test or perform confirmatory or perform reflex testing. In some situations, a minimum specimen volume may result in a QNS (quantity not sufficient) result, requiring a second specimen to be collected.
NOTE: Minimum volume does not allow for repeat analysis.
Reject Due To Identifies specimen types and conditions that may cause the specimen to be rejected
| Specimens other than | Serum |
| Anticoagulants other than | NA |
| Hemolysis | NA |
| Thawing | Warm reject; Cold reject |
| Lipemia | NA |
| Icteric | NA |
Specimen Stability Information Provides a description of the temperatures required to transport a specimen to the laboratory. Alternate acceptable temperature(s) are also included.
| Specimen Type | Temperature | Time |
|---|---|---|
| Serum | Frozen | 30 days |
Reference Values Describes reference intervals and additional information for interpretation of test results. May include intervals based on age and sex when appropriate. Intervals are Mayo-derived, unless otherwise designated. If an interpretive report is provided, the reference value field will state this.
Androstenedione
Units: ng/dL
Age Range
Premature (26-28w) Day 4 63 - 935
Premature (31-35w) Day 4 50 - 449
Full Term (1-7 days) <10 - 279
Levels decrease rapidly to a range of <52 ng/dL after one week.
1-11m <10 - 37
Androstenedione gradually decreases during the first six
months to prepubertal levels.
Prepubertal Children <10-17
Adult Males 44 - 186
Adult Females 28 - 230
Females Postmenopausal <10-93
Females
Tanner Stages Age (years) Range
1 <9.2 <10-17
2 9.2-13.7 <10-72
3 10.0-14.4 50-170
4 10.7-15.6 47-208
5 11.8-18.6 50-224
Males
Tanner Stages Age (years) Range
1 <9.8 <10-17
2 9.8-14.5 <10-33
3 10.7-15.4 17-72
4 11.8-16.2 15-115
5 12.8-17.3 33-192
Cortisol
Units: ug/dL
Age Range
Premature (26-28w) Day 4 1.0 - 11
Premature (31-35w) Day 4 2.5 - 9.1
Full Term Day 3 1.7 - 14
Full Term Day 7 2.0 - 11
31d - 11m 2.8 - 23
12m - 15y (8:00 AM) 3 .0 - 21
Adults
8:00 AM 8.0 - 19
4:00 PM 4.0 - 11
Deoxycorticosterone (DOC)
Units: ng/dL
Age Range
Premature (26 - 28w) Day 4 20 - 105
Premature (34 - 36w) Day 4 28 - 78
Newborn: Levels are markedly elevated at birth and
decrease rapidly during the first week to the range of
7 - 49 as found in older infants.
1 - 11m 7 - 49
Prepubertal Children 2 - 34
Pubertal Children
and Adults 8:00 AM 2 – 19
Dehydroepiandrosterone (DHEA)
Units: ng/dL
Age Range
1-5 yrs <68
6-7 yrs <111
8-10 yrs <186
11-12 yrs <202
13-14 yrs <319
15-16 yrs 39-481
17-19 yrs 40-491
20-49 yrs 31-701
> or = 50 yrs 21-402
11-Desoxycortisol
Units: ng/dL
Age Range
Premature (26-28w) Day 4 110 - 1376
Premature (31-35w) Day 4 48 - 579
Newborn Day 3 13 - 147
1 - 11m <10 - 156
Prepubertal 8:00 AM 20 - 155
Pubertal Children and
Adults 8:00 AM 12 - 158
17-OH Pregnenolone
Units: ng/dL
Age Range
Premature (26-28w) Day 4 375 - 3559
Premature (31-35w) Day 4 64 - 2380
3 Days 10 - 829
1 - 5m 36 - 763
6 - 11m 42 - 540
12 - 23m 14 - 207
24m - 5y 10 - 103
6 - 9y 10 - 186
Pubertal 44 - 235
Adults 53 - 357
Progesterone
Units: ng/dL
Males
Age Range
1-16y <10-15
Adults <10-11
Females
Age Range
1-10y <10-26
11y <10-255
12y <10-856
13y <10-693
14y <10-1204
15y <10-1076
16y <10-1294
Adult
Cycle Days Range
1-6 <10-17
7-12 <10-135
13-15 <10-1563
16-28 <10-2555
Post Menopausal <10
Note: Luteal progesterone peaked from 350 to 3750 ng/dL
on days ranging from 17 to 23.
17-Alpha-Hydroxyprogesterone
Units: ng/dL
Age Range
Premature (26-28w) Day 4 124 - 841
Premature (31-35w) Day 4 26 - 568
Full-Term Day 3 <78
Males: Levels increase after the first week to peak values
ranging from 40 - 200 between 30 and 60 days. Values then
decline to a prepubertal value of <91 before one year.
Prepubertal <91
Adult Males 27-199
Females
1 - 11m 13-106
Prepubertal <91
Adult Females
Follicular 15-70
Luteal 35-290
Females
Tanner Stages Age (years) Range
1 <9.2 <83
2 9.2-13.7 11-98
3 10.0-14.4 11-155
4 10.7-15.6 18-230
5 11.8-18.6 20-265
Males
Tanner Stages Age (years) Range
1 <9.8 <91
2 9.8-14.5 <116
3 10.7-15.4 10-138
4 11.8-16.2 29-180
5 12.8-17.3 24-175
Testosterone, Serum (Total)
Units: ng/dL
Age Range
Males
Premature (26-28w) Day 4 59 - 125
Premature (31-35w) Day 4 37 - 198
Newborns 75 - 400
1 - 7m: Levels decrease rapidly the first week to 20 - 50, then
increase to 60 - 400 between 20 - 60 days. Levels then decline
to prepubertal range levels of <2.5 - 10 by seven months.
Females
Premature (26 - 28w) Day 4 5 - 16
Premature (31 - 35w) Day 4 5 - 22
Newborns 20 - 64
1 - 7m: Levels decrease during the first month to less than 10
and remain there until puberty.
Prepubertal Males and Females <2.5 - 10
Adult Males >18 years 348 - 1197
Adult Females
Premenopausal: 10 - 55
Postmenopausal: 7 - 40
Males
Tanner Stage Age (years) Male
1 <9.8 <2.5 - 10
2 9.8 – 14.5 18 - 150
3 10.7 – 15.4 100 - 320
4 11.8 – 16.2 200 - 620
5 12.8 – 17.3 350 - 970
Females
Tanner Stage Age (years) Female
1 <9.2 <2.5 - 10
2 9.2 - 13.7 7 - 28
3 10.0 - 14.4 15 - 35
4 10.7 - 15.6 13 - 32
5 11.8 - 18.6 20 - 38
Test Performed By: Esoterix Endocrinology
4301 Lost Hills Rd
Calabasas Hills, CA 91301
Day(s) and Time(s) Test Performed Outlines the days and times the test is performed. This field reflects the day and time the sample must be in the testing laboratory to begin the testing process and includes any specimen preparation and processing time required before the test is performed. Some tests are listed as continuously performed, which means assays are performed several times during the day.
Monday, Wednesday
Analytic Time Defines the amount of time it takes the laboratory to setup and perform the test. This is defined in number of days. The shortest interval of time expressed is "same day/1 day," which means the results may be available the same day that the sample is received in the testing laboratory. One day means results are available 1 day after the sample is received in the laboratory.
Maximum Laboratory Time Defines the maximum time from specimen receipt at Mayo Medical Laboratories until the release of the test result
Performing Laboratory Location The location of the laboratory that performs the test
CPT Code Information Provides guidance in determining the appropriate Current Procedural Terminology (CPT) code(s) information for each test or profile. The listed CPT codes reflect Mayo Medical Laboratories interpretation of CPT coding requirements. It is the responsibility of each laboratory to determine correct CPT codes to use for billing.
82633/DOC
82634/Specific S
82157/Androstenedione
82533/Cortisol
82626/DHEA
84143/17-OH-Pregnenolone
84144/Progesterone
83498/17-OH-Progesterone
84403/Testosterone
LOINC® Code Information Provides guidance in determining the Logical Observation Identifiers Names and Codes (LOINC) values for the result codes returned for this test or profile.
| Result ID | Reporting Name | LOINC Code |
|---|---|---|
| Z1886 | Cortisol | In Process |
| Z0226 | Deoxycorticosterone (DOC) | In Process |
| Z1889 | Dehydroepiandrosterone (DHEA) | In Process |
| Z0227 | 11-Desoxycortisol (Spec Compound S) | In Process |
| Z1892 | 17-OH Pregnenolone | In Process |
| Z1894 | Progesterone | In Process |
| Z1897 | 17-Alpha-Hydroxyprogesterone | In Process |
| Z1901 | Androstenedione | In Process |
| Z1904 | Testosterone, Serum (Total) | In Process |
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