Test ID: FSINE
Sinemet , Serum/Plasma
Secondary ID 
A test code used for billing and in test definitions created prior to November 2011
NY State Approved Indicates the status of NY State approval and if the test is orderable for NY State clients.
Method Name A short description of the method used to perform the test
High-Performance Liquid Chromatography (HPLC)
Reporting Name A shorter/abbreviated version of the Published Name for a test; an abbreviated test name
Aliases Lists additional common names for a test, as an aid in searching
Levodopa/Carbidopa FORWARD
Sinemet FORWARD
Specimen Type Describes the specimen type needed for testing
Specimen Required Defines the optimal specimen. This field describes the type of specimen required to perform the test and the preferred volume to complete testing. The volume allows automated processing, fastest throughput and, when indicated, repeat or reflex testing.
Submit only 1 of the following specimens:
Serum
Draw blood in a plain, red-top tube(s). (Serum gel tube is not
acceptable.) Spin down and send 2 mL of serum frozen in a
plastic vial. Specimen must be frozen immediately or results will
be compromised.
Note: 1. Indicate serum on request form.
2. Label specimen appropriately (serum).
Plasma
Draw blood in a lavender-top (EDTA) tube(s). (Plasma gel tube is not
acceptable.) Spin down and send 2 mL of EDTA plasma frozen
in a plastic vial. Specimen must be frozen immediately or results
will be compromised.
Note: 1. Indicate plasma on request form.
2. Label specimen appropriately (plasma).
Specimen Minimum Volume Defines the amount of specimen required to perform an assay once, including instrument and container dead space. Submitting the minimum specimen volume makes it impossible to repeat the test or perform confirmatory or perform reflex testing. In some situations, a minimum specimen volume may result in a QNS (quantity not sufficient) result, requiring a second specimen to be collected.
Reject Due To Identifies specimen types and conditions that may cause the specimen to be rejected
| Specimens other than | Serum, plasma |
| Anticoagulants other than | Plain red-top, EDTA, heparin |
| Hemolysis | NA |
| Thawing | Warm reject; Cold reject |
| Lipemia | NA |
| Icteric | NA |
Specimen Stability Information Provides a description of the temperatures required to transport a specimen to the laboratory. Alternate acceptable temperature(s) are also included.
| Specimen Type | Temperature | Time |
|---|---|---|
| Varies | Frozen | 7 days |
Reference Values Describes reference intervals and additional information for interpretation of test results. May include intervals based on age and sex when appropriate. Intervals are Mayo-derived, unless otherwise designated. If an interpretive report is provided, the reference value field will state this.
Reporting limit determined each analysis.
Levodopa
Synonym(s): Sinemet Constituent
Carbidopa
Synonyms(s): Sinemet Constituent
Following a single oral dose of 100 mg Levodopa and 25 mg Carbidopa (conventional Sinemet tablet): Approximately 0.3 mcg Levodopa/mL and 0.05 mcg Carbidopa/mL plasma at 1 hour post dose. Average steady-state trough plasma levels in elderly patients following a regimen of Sinemet CR (50 mg Carbidopa and 200 mg Levodopa sustained release tablets) three times daily:
0.16 mcg Levodopa/mL
0.07 mcg Carbidopa/mL
Analysis by High Performance Liquid Chromatography (HPLC)
Test Performed By: NMS Labs
3701 Welsh Rd
PO Box 433A
Willow Grove, PA 19090-0437
Day(s) and Time(s) Test Performed Outlines the days and times the test is performed. This field reflects the day and time the sample must be in the testing laboratory to begin the testing process and includes any specimen preparation and processing time required before the test is performed. Some tests are listed as continuously performed, which means assays are performed several times during the day.
Tuesday
Analytic Time Defines the amount of time it takes the laboratory to setup and perform the test. This is defined in number of days. The shortest interval of time expressed is "same day/1 day," which means the results may be available the same day that the sample is received in the testing laboratory. One day means results are available 1 day after the sample is received in the laboratory.
Maximum Laboratory Time Defines the maximum time from specimen receipt at Mayo Medical Laboratories until the release of the test result
Specimen Retention Time Outlines the length of time after testing that a specimen is kept in the laboratory before it is discarded
Performing Laboratory Location The location of the laboratory that performs the test
CPT Code Information Provides guidance in determining the appropriate Current Procedural Terminology (CPT) code(s) information for each test or profile. The listed CPT codes reflect Mayo Medical Laboratories interpretation of CPT coding requirements. It is the responsibility of each laboratory to determine correct CPT codes to use for billing.
82491
LOINC® Code Information Provides guidance in determining the Logical Observation Identifiers Names and Codes (LOINC) values for the result codes returned for this test or profile.
| Result ID | Reporting Name | LOINC Code |
|---|---|---|
| Z1436 | Levodopa | 9385-6 |
| Z1872 | Reporting Limit | In Process |
| Z1456 | Carbidopa | 9328-6 |
| Z1879 | Reporting Limit | In Process |
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