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Test ID: FGIP
Gastric Inhibitory Polypeptide (GIP)

Secondary ID A test code used for billing and in test definitions created prior to November 2011

90171

NY State Approved Indicates the status of NY State approval and if the test is orderable for NY State clients.

No

Method Name A short description of the method used to perform the test

Direct Radioimmunoassay (RIA)

Reporting Name A shorter/abbreviated version of the Published Name for a test; an abbreviated test name

Gastric Inhibitory Polypeptide

Aliases Lists additional common names for a test, as an aid in searching

Gastric Inhibitory Polypeptide (GIP) FORWARD
GIP (Gastric Inhibitory Polypeptide) FORWARD
Glucose-Dependent Insulinotropic Peptide FORWARD

Specimen Type Describes the specimen type needed for testing

GI Plasma

Specimen Required Defines the optimal specimen. This field describes the type of specimen required to perform the test and the preferred volume to complete testing. The volume allows automated processing, fastest throughput and, when indicated, repeat or reflex testing.

Collect 10 mL of blood in special tube containing G.I. Preservative (MML supply number T125). Specimen should be separated and 3 mL plasma frozen as soon as possible.

Patient preparation:

1. Patient should be fasting 10-12 hours prior to collection.

2. Antacid medication or medications that affect intestinal motility or Insulin secretion should be discontinued, if possible, for at least 48 hours prior to specimen collection.

Specimen Minimum Volume Defines the amount of specimen required to perform an assay once, including instrument and container dead space. Submitting the minimum specimen volume makes it impossible to repeat the test or perform confirmatory or perform reflex testing. In some situations, a minimum specimen volume may result in a QNS (quantity not sufficient) result, requiring a second specimen to be collected.

1 mL

Reject Due To Identifies specimen types and conditions that may cause the specimen to be rejected

Specimens other than

Plasma

Anticoagulants other than

Special GI preservative (MML supply T125)

Hemolysis

NA

Thawing

Warm reject; Cold reject

Lipemia

NA

Icteric

NA

Specimen Stability Information Provides a description of the temperatures required to transport a specimen to the laboratory. Alternate acceptable temperature(s) are also included.

Specimen TypeTemperatureTime
GI PlasmaFrozen180 days

Clinical Information Discusses physiology, pathophysiology, and general clinical aspects, as they relate to a laboratory test

Gastric Inhibitory Peptide is a 43 amino acid peptide structurally related to Glucagon and Secretin and is found in the mucosa of upper intestine produced by K cells. GIP was originally detected as a factor inhibiting the secretion of gastric acid and Gastrin secretion. Its major action has now been determined to be a potent stimulant of B cells to release Insulin and is also known as Glucose-Dependent Insulinotropic Peptide. Exaggerated increases in GIP are noted after glucose administration to patients with Pancreatitis. This increase is also seen in patients with Diabetes Mellitus. GIP levels are decreased by Calcitonin.  Elevated levels are present in cases of Verner-Morrison Syndrome.

Reference Values Describes reference intervals and additional information for interpretation of test results. May include intervals based on age and sex when appropriate. Intervals are Mayo-derived, unless otherwise designated. If an interpretive report is provided, the reference value field will state this.

Fasting:  Up to 50 pg/ml

Postprandial:  110 - 720 pg/ml

 

Test Performed by: Inter Science Institute

                            944 West Hyde Park

                            Inglewood, CA  90302

Cautions Discusses conditions that may cause diagnostic confusion, including improper specimen collection and handling, inappropriate test selection, and interfering substances

No significant cautionary statements.

Day(s) and Time(s) Test Performed Outlines the days and times the test is performed. This field reflects the day and time the sample must be in the testing laboratory to begin the testing process and includes any specimen preparation and processing time required before the test is performed. Some tests are listed as continuously performed, which means assays are performed several times during the day.

Monday through Friday

Analytic Time Defines the amount of time it takes the laboratory to setup and perform the test. This is defined in number of days. The shortest interval of time expressed is "same day/1 day," which means the results may be available the same day that the sample is received in the testing laboratory. One day means results are available 1 day after the sample is received in the laboratory.

14 days

Maximum Laboratory Time Defines the maximum time from specimen receipt at Mayo Medical Laboratories until the release of the test result

16 - 20 days

Performing Laboratory Location The location of the laboratory that performs the test

Inter Science Institute

Test Classification Provides information regarding the medical device classification for laboratory test kits and reagents. Tests may be classified as cleared or approved by the US Food and Drug Administration (FDA) and used per manufacturer's instructions, or as products that do not undergo full FDA review and approval, and are then labeled as an Analyte Specific Reagent (ASR), Investigation Use Only (IUO) product, or a Research Use Only (RUO) product.

This test was performed using a kit that has not been cleared or approved by the FDA and is designated as research use only. The analytic performance characteristics of this test have been determined by Inter Science Institute. This test is not intended for diagnosis or patient management decisions without confirmation by other medically established means.

CPT Code Information Provides guidance in determining the appropriate Current Procedural Terminology (CPT) code(s) information for each test or profile. The listed CPT codes reflect Mayo Medical Laboratories interpretation of CPT coding requirements. It is the responsibility of each laboratory to determine correct CPT codes to use for billing.

83519

LOINC® Code Information Provides guidance in determining the Logical Observation Identifiers Names and Codes (LOINC) values for the result codes returned for this test or profile.

Result IDReporting NameLOINC Code
Z0932Gastric Inhibitory PolypeptideIn Process