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Test ID: STRIC
Trichinella Antibody, Serum

Secondary ID A test code used for billing and in test definitions created prior to November 2011

9017

NY State Approved Indicates the status of NY State approval and if the test is orderable for NY State clients.

Yes

Useful For Suggests clinical disorders or settings where the test may be helpful

As an adjunct in the diagnosis of trichinosis

Method Name A short description of the method used to perform the test

Enzyme-Linked Immunosorbent Assay (ELISA)

Reporting Name A shorter/abbreviated version of the Published Name for a test; an abbreviated test name

Trichinella Ab, S

Aliases Lists additional common names for a test, as an aid in searching

Agglutination for Trichinosis
Latex Test for Trichinosis
Parasite Serologies-done by clinic
Trichina Agglutination
TRICHINOSIS ANTIBOY
Trichinosis Latex Agglutination

Specimen Type Describes the specimen type needed for testing

Serum

Specimen Required Defines the optimal specimen. This field describes the type of specimen required to perform the test and the preferred volume to complete testing. The volume allows automated processing, fastest throughput and, when indicated, repeat or reflex testing.

Container/Tube:

Preferred: Red top

Acceptable: Serum gel

Specimen Volume: 0.5 mL

Specimen Minimum Volume Defines the amount of specimen required to perform an assay once, including instrument and container dead space. Submitting the minimum specimen volume makes it impossible to repeat the test or perform confirmatory or perform reflex testing. In some situations, a minimum specimen volume may result in a QNS (quantity not sufficient) result, requiring a second specimen to be collected.

0.15 mL

Reject Due To Identifies specimen types and conditions that may cause the specimen to be rejected

Hemolysis

Mild OK; Gross reject

Lipemia

Mild OK; Gross reject

Icterus

NA

Other

NA

Specimen Stability Information Provides a description of the temperatures required to transport a specimen to the laboratory. Alternate acceptable temperature(s) are also included.

Specimen TypeTemperatureTime
SerumFrozen (preferred)5 days
 Refrigerated 5 days

Clinical Information Discusses physiology, pathophysiology, and general clinical aspects, as they relate to a laboratory test

Trichinosis is an infection by the nematode parasite, Trichinella spiralis. The infection is acquired by ingestion of larvae in inadequately cooked, contaminated meat, especially pork, bear and walrus meat may also be sources of infection.

 

After ingestion, acid-pepsin digestion in the stomach liberates the larvae which develop into adult worms in the small intestine. After fertilization, the female worm produces larvae which penetrate the mucosa and seed the skeletal muscles via the blood stream. In muscle fibers they coil and encyst remaining viable for up to several years.

 

Diarrhea is the most common symptom associated with intestinal infection with adult worms. Subsequently, during systemic invasion by the larvae, fever, periorbital swelling, muscle pain and swelling, and pulmonary symptoms and rash develop.

Reference Values Describes reference intervals and additional information for interpretation of test results. May include intervals based on age and sex when appropriate. Intervals are Mayo-derived, unless otherwise designated. If an interpretive report is provided, the reference value field will state this.

Negative (reported as positive or negative)

Interpretation Provides information to assist in interpretation of the test results

A positive enzyme-linked immunosorbent assay (ELISA) suggests current infection with Trichinella spiralis. Serology should be used in conjunction with clinical, epidemiologic, and other laboratory tests to establish the correct diagnosis.

 

The number of individuals showing positive results may vary significantly between populations and geographic regions.

Cautions Discusses conditions that may cause diagnostic confusion, including improper specimen collection and handling, inappropriate test selection, and interfering substances

Antibodies to Trichinella spiralis may not be detectable until 3 weeks after the onset of infection. Therefore, negative results in suspicious cases should be followed by repeat testing in several weeks.

Clinical Reference Provides recommendations for further in-depth reading of a clinical nature

Grove DI: Tissue nematodes. In Principles and Practice of Infectious Diseases. 4th edition. Edited by GL Mandell, et al. New York, Churchill Livingstone, 1995

Method Description Describes how the test is performed and provides a method-specific reference

The patient's serum is diluted 1:64 and 100 uL is placed in microtiter plate wells which have been coated with Trichinella spiralis excretory-secretory antigens. After 10 minutes of incubation, the wells are washed and a protein-horseradish peroxidase reagent is added. Color development occurs after addition of peroxide and the tetramethylbenzidine chromogen. The reaction can be read visually or with the aid of a spectrophotometer. (Maddison SE: Serodiagnosis of parasitic diseases. Clin Microbiol Rev 1991;4:457-469)

Day(s) and Time(s) Test Performed Outlines the days and times the test is performed. This field reflects the day and time the sample must be in the testing laboratory to begin the testing process and includes any specimen preparation and processing time required before the test is performed. Some tests are listed as continuously performed, which means assays are performed several times during the day.

Tuesday, Thursday; 9 a.m.

Analytic Time Defines the amount of time it takes the laboratory to setup and perform the test. This is defined in number of days. The shortest interval of time expressed is "same day/1 day," which means the results may be available the same day that the sample is received in the testing laboratory. One day means results are available 1 day after the sample is received in the laboratory.

1 day

Maximum Laboratory Time Defines the maximum time from specimen receipt at Mayo Medical Laboratories until the release of the test result

7 days

Specimen Retention Time Outlines the length of time after testing that a specimen is kept in the laboratory before it is discarded

14 days

Performing Laboratory Location The location of the laboratory that performs the test

Rochester

Test Classification Provides information regarding the medical device classification for laboratory test kits and reagents. Tests may be classified as cleared or approved by the US Food and Drug Administration (FDA) and used per manufacturer's instructions, or as products that do not undergo full FDA review and approval, and are then labeled as an Analyte Specific Reagent (ASR), Investigation Use Only (IUO) product, or a Research Use Only (RUO) product.

This test has been cleared or approved by the U.S. Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.

CPT Code Information Provides guidance in determining the appropriate Current Procedural Terminology (CPT) code(s) information for each test or profile. The listed CPT codes reflect Mayo Medical Laboratories interpretation of CPT coding requirements. It is the responsibility of each laboratory to determine correct CPT codes to use for billing.

86784

LOINC® Code Information Provides guidance in determining the Logical Observation Identifiers Names and Codes (LOINC) values for the result codes returned for this test or profile.

Result IDReporting NameLOINC Code
9017Trichinella Ab, S19253-4