Test ID: FGNRH
Gonadotropin Releasing Hormone (Gn-RH)
Secondary ID 
A test code used for billing and in test definitions created prior to November 2011
NY State Approved Indicates the status of NY State approval and if the test is orderable for NY State clients.
Method Name A short description of the method used to perform the test
Direct Radioimmunoassay (RIA)
Reporting Name A shorter/abbreviated version of the Published Name for a test; an abbreviated test name
Aliases Lists additional common names for a test, as an aid in searching
Gonadotropin Releasing Hormone (Gn-RH) FORWARD
LHRH FORWARD
Luteinizing Hormone-Releasing Hormone FORWARD
Specimen Type Describes the specimen type needed for testing
Specimen Required Defines the optimal specimen. This field describes the type of specimen required to perform the test and the preferred volume to complete testing. The volume allows automated processing, fastest throughput and, when indicated, repeat or reflex testing.
Submit only 1 of the following specimens:
Serum
Draw blood in a plain, red-top or serum-gel tube(s). Separate
immediately and send 3 mL of serum frozen in a plastic vial.
Note: 1. Indicate serum on request form.
2. Label specimen appropriately (serum).
Plasma
Draw blood in a lavender-top (EDTA) tube(s). Separate immediately
and send 3 mL of EDTA plasma frozen in a plastic vial.
Note: 1. Indicate plasma on request form.
2. Label specimen appropriately (plasma).
Patient preparation:
Patient should not be on any Steroid, ACTH, Gonadotropin,
or Estrogen medications, if possible, for at least 48 hours
prior to collection.
Specimen Minimum Volume Defines the amount of specimen required to perform an assay once, including instrument and container dead space. Submitting the minimum specimen volume makes it impossible to repeat the test or perform confirmatory or perform reflex testing. In some situations, a minimum specimen volume may result in a QNS (quantity not sufficient) result, requiring a second specimen to be collected.
Reject Due To Identifies specimen types and conditions that may cause the specimen to be rejected
| Specimens other than | Serum, plasma |
| Anticoagulants other than | EDTA |
| Hemolysis | NA |
| Thawing | Warm reject; Cold reject |
| Lipemia | NA |
| Icteric | NA |
Specimen Stability Information Provides a description of the temperatures required to transport a specimen to the laboratory. Alternate acceptable temperature(s) are also included.
| Specimen Type | Temperature | Time |
|---|---|---|
| Varies | Frozen | 365 days |
Clinical Information Discusses physiology, pathophysiology, and general clinical aspects, as they relate to a laboratory test
Gonadotropin-Releasing Hormone (Gn-RH), also known as
Luteinizing Hormone-Releasing Hormone (LH-RH), is a decapeptide
secreted pulsatily from the hypothalamus. It stimulates the release of
the Gonadotropins - Luteinizing Hormone and Follicle Stimulating
Hormone - exerting a stronger effect on Luteinizing Hormone.
Testosterone and Estradiol, whose release is stimulated by the
Gonadotropins, exert a negative feedback control on LH-RH both at
the hypothalamic site and by decreasing pituitary receptor binding.
LH-RH levels are low in patients with hypothalamic hypogonadism
differentiating them from the high levels usually found in primary
hypopituitary hypogonadism. Accentuation of the LH-RH pulse
occurs at the onset of puberty triggering the release of LH and FSH
required in pubertal development. LH-RH is stimulated by Epinephrine
and suppressed by Dopamine and opiates. LH-RH and some of its
agonists are frequently used to induce ovulation.
Reference Values Describes reference intervals and additional information for interpretation of test results. May include intervals based on age and sex when appropriate. Intervals are Mayo-derived, unless otherwise designated. If an interpretive report is provided, the reference value field will state this.
Adult Reference Range(s):
Males: 4.0-8.0 pg/mL
Females: 2.0-10.0 pg/mL
Test Performed by: Inter Science Institute
944 West Hype Park
Inglewood, CA 90302
Day(s) and Time(s) Test Performed Outlines the days and times the test is performed. This field reflects the day and time the sample must be in the testing laboratory to begin the testing process and includes any specimen preparation and processing time required before the test is performed. Some tests are listed as continuously performed, which means assays are performed several times during the day.
Monday through Friday
Analytic Time Defines the amount of time it takes the laboratory to setup and perform the test. This is defined in number of days. The shortest interval of time expressed is "same day/1 day," which means the results may be available the same day that the sample is received in the testing laboratory. One day means results are available 1 day after the sample is received in the laboratory.
Maximum Laboratory Time Defines the maximum time from specimen receipt at Mayo Medical Laboratories until the release of the test result
Performing Laboratory Location The location of the laboratory that performs the test
Test Classification Provides information regarding the medical device classification for laboratory test kits and reagents. Tests may be classified as cleared or approved by the US Food and Drug Administration (FDA) and used per manufacturer's instructions, or as products that do not undergo full FDA review and approval, and are then labeled as an Analyte Specific Reagent (ASR), Investigation Use Only (IUO) product, or a Research Use Only (RUO) product.
CPT Code Information Provides guidance in determining the appropriate Current Procedural Terminology (CPT) code(s) information for each test or profile. The listed CPT codes reflect Mayo Medical Laboratories interpretation of CPT coding requirements. It is the responsibility of each laboratory to determine correct CPT codes to use for billing.
83727
LOINC® Code Information Provides guidance in determining the Logical Observation Identifiers Names and Codes (LOINC) values for the result codes returned for this test or profile.
| Result ID | Reporting Name | LOINC Code |
|---|---|---|
| Z0929 | Gonadotropin Releasing Hormone | 13660-6 |
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