Test ID: HMSU
Heavy Metals Screen, 24 Hour, Urine
Secondary ID 
A test code used for billing and in test definitions created prior to November 2011
NY State Approved Indicates the status of NY State approval and if the test is orderable for NY State clients.
Profile Information A profile is a group of laboratory tests that are ordered and performed together under a single Mayo Test ID. Profile information lists the test performed, inclusive of the test fee, when a profile is ordered and includes reporting names and individual availability.
| Test ID | Reporting Name | Available Separately | Always Performed |
|---|---|---|---|
| ASHMS | Arsenic, 24 Hr, U | Yes, (order ASU) | Yes |
| PBS | Lead, 24 Hr, U | Yes, (order PBU) | Yes |
| CDHMU | Cadmium, 24 Hr, U | Yes, (order CDU) | Yes |
| HGHMS | Mercury, 24 Hr, U | Yes, (order HGU) | Yes |
Special Instructions and Forms Describes specimen collection and preparation information, test algorithms, and other information pertinent to test. Also includes pertinent information and consent forms to be used when requesting a particular test
Method Name A short description of the method used to perform the test
Inductively Coupled Plasma-Mass Spectrometry (ICP-MS)
Reporting Name A shorter/abbreviated version of the Published Name for a test; an abbreviated test name
Aliases Lists additional common names for a test, as an aid in searching
As (Arsenic)
Cadmium (Cd)
Cd (Cadmium)
Hg (Mercury)
Lead (Pb)
Mercury (Hg)
Metals Screens
Pb (Lead)
Toxicology Quantitative Screen, Metals
Specimen Type Describes the specimen type needed for testing
Specimen Required Defines the optimal specimen. This field describes the type of specimen required to perform the test and the preferred volume to complete testing. The volume allows automated processing, fastest throughput and, when indicated, repeat or reflex testing.
Collection Container/Tube: Clean, plastic aliquot container with no metal cap or glued insert
Submission Container/Tube: Plastic, 10-mL urine tube (Supply T068)
Specimen Volume: 10 mL
Collection Instructions:
1. Collect urine for 24 hours.
2. No preservative.
3. See Metals Analysis-Collection and Transport in Special Instructions for complete instructions.
4. Refrigerate specimen within 4 hours of completion of 24-hour collection.
Additional Information:
1. 24-Hour volume is required.
2. See Urine Preservatives in Special Instructions for multiple collections.
3. Patient should not eat seafood for a 48-hour period prior to start of collection.
4. High concentrations of gadolinium and iodine are known to interfere with most metals tests. If either gadolinium-or iodine-containing contrast media has been administered, a specimen should not be collected for 96 hours.
Urine Preservative Collection Options
| Ambient | No |
| Refrigerated | Preferred |
| Frozen | Yes |
| 6N HCl | Yes |
| 50% Acetic Acid | Yes |
| Na2CO3 | No |
| Toluene | Yes |
| 6N HNO3 | No |
| Boric Acid | No |
| Thymol | No |
Specimen Minimum Volume Defines the amount of specimen required to perform an assay once, including instrument and container dead space. Submitting the minimum specimen volume makes it impossible to repeat the test or perform confirmatory or perform reflex testing. In some situations, a minimum specimen volume may result in a QNS (quantity not sufficient) result, requiring a second specimen to be collected.
Reject Due To Identifies specimen types and conditions that may cause the specimen to be rejected
| Hemolysis | NA |
| Lipemia | NA |
| Icterus | NA |
| Other | NA |
Specimen Stability Information Provides a description of the temperatures required to transport a specimen to the laboratory. Alternate acceptable temperature(s) are also included.
| Specimen Type | Temperature | Time |
|---|---|---|
| Urine | Refrigerated (preferred) | 7 days |
| Frozen | 7 days |
Clinical Information Discusses physiology, pathophysiology, and general clinical aspects, as they relate to a laboratory test
See individual test descriptions for:
-ASHMS/8644 Arsenic, 24 Hour, Urine
-CDHMU/8678 Cadmium, 24 Hour, Urine
-PBS/8600 Lead, 24 Hour, Urine
-HGHMS/8592 Mercury, 24 Hour, Urine
Reference Values Describes reference intervals and additional information for interpretation of test results. May include intervals based on age and sex when appropriate. Intervals are Mayo-derived, unless otherwise designated. If an interpretive report is provided, the reference value field will state this.
ARSENIC
0-35 mcg/specimen
Reference values apply to all ages.
LEAD
0-4 mcg/specimen
Reference values apply to all ages.
CADMIUM
0-15 years: not established
> or =16 years: 0.0-1.3 mcg/specimen
MERCURY
0-15 years: not established
> or =16 years: 0-9 mcg/specimen
Toxic concentration: >50 mcg/specimen
The concentration at which toxicity is expressed is widely variable between patients. 50 mcg/specimen is the lowest concentration at which toxicity is usually apparent.
Cautions Discusses conditions that may cause diagnostic confusion, including improper specimen collection and handling, inappropriate test selection, and interfering substances
High concentrations of gadolinium and iodine are known to interfere with most metals tests. If either gadolinium- or iodine-containing contrast media has been administered, a specimen should not be collected for 96 hours.
Method Description Describes how the test is performed and provides a method-specific reference
See individual test descriptions for:
-ASHMS/8644 Arsenic, 24 Hour, Urine
-CDHMU/8678 Cadmium, 24 Hour, Urine
-PBS/8600 Lead, 24 Hour, Urine
-HGHMS/8592 Mercury, 24 Hour, Urine
Day(s) and Time(s) Test Performed Outlines the days and times the test is performed. This field reflects the day and time the sample must be in the testing laboratory to begin the testing process and includes any specimen preparation and processing time required before the test is performed. Some tests are listed as continuously performed, which means assays are performed several times during the day.
Monday through Friday; 3 p.m. - 9 p.m.; Saturday; 8 a.m. – 3 p.m./Continuously
Analytic Time Defines the amount of time it takes the laboratory to setup and perform the test. This is defined in number of days. The shortest interval of time expressed is "same day/1 day," which means the results may be available the same day that the sample is received in the testing laboratory. One day means results are available 1 day after the sample is received in the laboratory.
Maximum Laboratory Time Defines the maximum time from specimen receipt at Mayo Medical Laboratories until the release of the test result
Specimen Retention Time Outlines the length of time after testing that a specimen is kept in the laboratory before it is discarded
Performing Laboratory Location The location of the laboratory that performs the test
Test Classification Provides information regarding the medical device classification for laboratory test kits and reagents. Tests may be classified as cleared or approved by the US Food and Drug Administration (FDA) and used per manufacturer's instructions, or as products that do not undergo full FDA review and approval, and are then labeled as an Analyte Specific Reagent (ASR), Investigation Use Only (IUO) product, or a Research Use Only (RUO) product.
CPT Code Information Provides guidance in determining the appropriate Current Procedural Terminology (CPT) code(s) information for each test or profile. The listed CPT codes reflect Mayo Medical Laboratories interpretation of CPT coding requirements. It is the responsibility of each laboratory to determine correct CPT codes to use for billing.
82175-Arsenic
82300-Cadmium
83655-Lead
83825-Mercury
LOINC® Code Information Provides guidance in determining the Logical Observation Identifiers Names and Codes (LOINC) values for the result codes returned for this test or profile.
| Result ID | Reporting Name | LOINC Code |
|---|---|---|
| 8678 | Cadmium, 24 Hr, U | 5612-7 |
| 8644 | Arsenic, 24 Hr, U | 5587-1 |
| 2549 | Mercury, 24 Hr, U | 6693-6 |
| 8600 | Lead, 24 Hr, U | 5677-0 |
| 2548 | Pb Concentration | In Process |
| 26627 | Hg Concentration | 21383-5 |
| 2547 | As Concentration | In Process |
| TIME4 | Collection Duration | 13362-9 |
| VL16 | Total Volume | 28009-9 |
| 2654 | Cd Concentration | 21130-0 |
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